Quantification of cilnidipine in human plasma by liquid chromatography-mass spectrometry

KR Lee, YJ Chae, JH Lee, DD Kim… - Journal of liquid …, 2012 - Taylor & Francis
A liquid chromatography-mass spectrometry (LC-MS) assay was developed and validated
for the quantification of cilnidipine, a calcium channel antagonist, in human plasma. Plasma …

Determination of cilnidipine, a new calcium antagonist, in human plasma using high performance liquid chromatography with tandem mass spectrometric detection

X Zhang, S Zhai, R Zhao, J Ouyang, X Li… - Analytica chimica …, 2007 - Elsevier
A rapid, sensitive and reliable high performance liquid chromatographic method coupled
with tandem mass spectrometry (HPLC–MS/MS) has been developed and validated for the …

Development of a liquid chromatography/negative-ion electrospray tandem mass spectrometry assay for the determination of cilnidipine in human plasma and its …

HW Lee, JH Seo, HS Lee, SY Jeong, YW Cho… - … of Chromatography B, 2008 - Elsevier
A simple method using a one-step liquid–liquid extraction (LLE) with methyl-t-butyl ether
(MTBE) followed by high-performance liquid chromatography (HPLC) with negative-ion …

[PDF][PDF] Analytical methodologies for determination of Cilnidipine: An overview

KS Kokilambigai, KS Lakshmi - Int J Pharm Pharm Sci, 2014 - scholar.archive.org
Cilnidipine is a dual blocker of L-type voltage-gated calcium channels in vascular smooth
muscle and N-type calcium channels in sympathetic nerve terminals that supply blood …

[PDF][PDF] Determination of cilnidipine from pharmaceutical formulation by high performance thin layer chromatographic method

HS Karmalkar, VV Vaidya, NA Gomes… - Analytical …, 2008 - hakon-art.com
Cilnidipine [1] is a dihydropyridine (DHP) type of calcium channel antagonist. Unlike other
calcium channel antagonists, cilnidipine blocks the influx of Ca2+ ions into both vascular …

[PDF][PDF] A review: analytical methods for determination of cilnidipine in biological fluid and pharmaceutical dosage forms

FV Buchiya, V Jain, H Raj - Pharma, 2014 - academia.edu
Cilnidipine is act as a dual blocker by blocking L-type of calcium channel present in vascular
smooth muscles and N-type of calcium channel present in sympathetic nerve terminal that …

Development and validation of stability indicating RP-HPLC method for estimation of Cilnidipine

B Tiwari, MK Shirsat, A Kulkarni - Journal of Drug Delivery and …, 2020 - jddtonline.info
Cilnidipine is one of the dihydropyridine calcium antagonists. It was created combinedly by
Fuji Viscera Pharmaceutical Company, Ajinomoto and Japan and was approved in the year …

Selective and rapid liquid chromatography-mass spectrometry method for the determination of lercanidipine in human plasma

II Salem, J Idrees, JI Al Tamimi, P Farina - Journal of Chromatography B, 2004 - Elsevier
A specific liquid chromatography–mass spectrometric (LC–MS/MS) assay was developed
and validated for the determination of lercanidipine, a dihydropyridine calcium channel …

[PDF][PDF] Development and validation of novel UV and RP-HPLC methods for determination of cilnidipine (a new generation ca channel blocker) in pharmaceutical …

PR Sankar, V Swathi, PS Babu - Int J Pharm Sci Res, 2019 - academia.edu
An accurate and precise High-Performance Reversed-Phase Liquid Chromatographic and
UV spectrophotometric methods were developed and validated for the quantitative …

Development and validation of a Rapid Stability Indicating chromatographic determination of Cilnidipine in Bulk and Dosage form.

M Safhi, MY Nagaraj - Research Journal of Pharmacy and …, 2013 - indianjournals.com
A rapid, simple and specific reversed-phase HPLC method has been developed for
estimation of Cilnidipine in Pharmaceutical Formulation. HPLC analysis was performed on a …