Aromatase enzyme activity during gonadal sex differentiation in alligator embryos

CA Smith, PK Elf, JW Lang, JMP Joss - Differentiation, 1995 - Elsevier
Sexual differentiation of the gonads in Alligator mississippiensis and many other oviparous
reptiles is controlled by egg incubation temperature. Estrogens are thought to play a role in …

Alligator aromatase cDNA sequence and its expression in embryos at male and female incubation temperatures

WN Gabriel, B Blumberg, S Sutton… - Journal of …, 2001 - Wiley Online Library
In all species of crocodilians, sex is determined not by genetic mechanisms, but by the
temperature at which the egg is incubated. In the American alligator (Alligator …

Yolk steroids decline during sexual differentiation in the alligator

AJ Conley, P Elf, CJ Corbin, S Dubowsky… - General and …, 1997 - Elsevier
The leading explanation of temperature-dependent sex determination (TSD) in reptiles
postulates that (1) ovarian differentiation is directed by estrogen and that (2) estrogen is …

Effects of incubation temperature and estrogen exposure on aromatase activity in the brain and gonads of embryonic alligators.

MR Milnes Jr, RN Roberts… - Environmental Health …, 2002 - ehp.niehs.nih.gov
During embryogenesis, incubation temperature and the hormonal environment influence
gonadal differentiation of some reptiles, including all crocodilians. Current evidence …

Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor

VA Lance, MH Bogart - General and Comparative Endocrinology, 1992 - Elsevier
It has been suggested that sex differentiation in vertebrates is steroid hormone dependent,
that estrogens play a critical role in ovarian differentiation, and that male sex differentiation …

Cloning and expression of aromatase in a turtle with temperature-dependent sex determination

C Murdock, T Wibbels - General and comparative endocrinology, 2003 - Elsevier
It has been hypothesized that estrogen production may play a pivotal role in the sex
determination of reptiles with temperature-dependent sex determination (TSD). This …

Embryonic brain‐gonadal axis in temperature‐dependent sex determination of reptiles: A role for P450 aromatase (CYP19)

P Jeyasuria, AR Place - Journal of Experimental Zoology, 1998 - Wiley Online Library
Sex determination in egg‐laying amniotes may be fundamentally different from that of
placental mammals. The mammalian ovary differentiates normally in the absence of …

Is regulation of aromatase expression in reptiles the key to understanding temperature‐dependent sex determination?

VA Lance - Journal of Experimental Zoology Part A: Ecological …, 2009 - Wiley Online Library
A brief review of our current understanding (or lack of understanding) of the molecular basis
of temperature‐dependent sex determination (TSD) in reptiles is presented. Current theories …

Temperature variation and sex determination in reptiles

C Pieau - BioEssays, 1996 - Wiley Online Library
In many species of reptiles, sex is determined at fertilization by zygotic sex chromosome
composition. In other species, including all crocodilians, most turtles and some lizards, sex is …

Temperature-dependent aromatase expression in developing diamondback terrapin (Malaclemys terrapin) embryos

P Jeyasuria, AR Place - The Journal of steroid biochemistry and molecular …, 1997 - Elsevier
In the diamondback terrapin, Malaclemys terrapin, males hatch at incubation temperatures
below 28° C whereas females hatch at temperatures above 30° C. When estrogen is applied …