Real-world outcomes and clinical predictors of immune checkpoint inhibitor monotherapy in advanced lung cancer

S Zhang, DF Pease, AA Kulkarni… - Clinical Medicine …, 2021 - journals.sagepub.com
Background: Immune checkpoint inhibitors (ICIs) have changed the treatment paradigm of
advanced-stage non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC) …

[HTML][HTML] Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer

B Duchemann, J Remon, M Naigeon… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICI) have been validated as an effective new treatment
strategy in several tumoral types including lung cancer. This remarkable shift in the …

[PDF][PDF] Immunotherapy for non-small cell lung cancer: current landscape and future perspectives

SM Lim, MH Hong, HR Kim - Immune Network, 2020 - synapse.koreamed.org
Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of
patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective …

Primary and acquired resistance to immunotherapy in lung cancer: unveiling the mechanisms underlying of immune checkpoint blockade therapy

L Boyero, A Sánchez-Gastaldo, M Alonso… - Cancers, 2020 - mdpi.com
Simple Summary Immuno-oncology has redefined the treatment of lung cancer, with the
ultimate goal being the reactivation of the anti-tumor immune response. This has led to the …

Immune checkpoint immunotherapy for non-small cell lung cancer: benefits and pulmonary toxicities

K Suresh, J Naidoo, CT Lin, S Danoff - Chest, 2018 - Elsevier
Immune checkpoint inhibitors (ICIs) are newer, immunotherapy-based drugs that have been
shown to improve survival in advanced non-small cell lung cancer (NSCLC). Unlike …

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC)

JR Brahmer, R Govindan, RA Anders… - … for immunotherapy of …, 2018 - Springer
Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small cell
lung cancer (NSCLC) accounting for over 85% of all cases. Until recently, chemotherapy …

Immune checkpoint inhibitors in advanced non–small cell lung cancer

HI Assi, AO Kamphorst, NM Moukalled… - Cancer, 2018 - Wiley Online Library
The emergence of immune checkpoint inhibitors for the treatment of cancer has led to major
changes to the therapeutic landscape of lung cancer. Improvements in overall survival …

The landscape of immune checkpoint inhibitor plus chemotherapy versus immunotherapy for advanced non‐small‐cell lung cancer: a systematic review and meta …

C Wang, W Qiao, Y Jiang, M Zhu, J Shao… - Journal of cellular …, 2020 - Wiley Online Library
Background Lung cancer is the leading cause of cancer‐related deaths worldwide and the
prognosis remains poor. The recent introduction of the immune checkpoint inhibitor (ICI), or …

Comparative efficacy and safety of first‐line treatments for advanced non‐small cell lung cancer with immune checkpoint inhibitors: a systematic review and meta …

R Chen, X Hou, L Yang, D Zhao - Thoracic Cancer, 2019 - Wiley Online Library
Background Non‐small cell lung cancer (NSCLC) is the predominant type of lung cancer,
and most clinically curable patients are diagnosed with locally advanced disease. Although …

Immunotherapy in lung cancer: From a minor god to the Olympus

A Russo, MG McCusker, KA Scilla, KE Arensmeyer… - Immunotherapy, 2020 - Springer
Over the last decade, we have witnessed a paradigm shift in cancer treatment, with the
advent of novel therapeutic approaches that target or manipulate the immune system, also …