Immuno-oncology—the new paradigm of lung cancer treatment

DE Dawe, CH Harlos, RA Juergens - Current Oncology, 2020 - mdpi.com
Systemic therapy is an essential part of treatment for all patients with small-cell lung cancer
(sclc) and for most patients with non-small-cell lung cancer (nsclc). Standards of care have …

Resistance to immune checkpoint inhibitors in advanced lung cancer: Clinical characteristics, potential prognostic factors and next strategy

J Zhou, X Lu, H Zhu, N Ding, Y Zhang, X Xu… - Frontiers in …, 2023 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) have shown unprecedented clinical benefit
in cancer immunotherapy and are rapidly transforming the practice of advanced lung cancer …

Highlights on immune checkpoint inhibitors in non–small cell lung cancer

M Shen, X Ren - Tumor Biology, 2017 - journals.sagepub.com
The treatment of advanced or refractory non–small cell lung cancer has been historically
difficult owing to the lack of studies on effective systemic cure. The progress in lung cancer …

Achievements and futures of immune checkpoint inhibitors in non-small cell lung cancer

Z Qiu, Z Chen, C Zhang, W Zhong - Experimental hematology & oncology, 2019 - Springer
Non-small cell lung cancer (NSCLC) has been threatening human health for years.
Cytotoxicity-based chemotherapy seems to reach plateau in NSCLC treatment …

[HTML][HTML] New advances in immunotherapy for non-small cell lung cancer

H Qin, F Wang, H Liu, Z Zeng, S Wang… - American journal of …, 2018 - ncbi.nlm.nih.gov
Immunotherapy is one of the methods that can change the survival rate of patients with
malignant tumors, in addition to surgery therapy, radiotherapy, chemotherapy and targeted …

Lung cancer immunotherapy: Beyond common immune checkpoints inhibitors

M Catalano, S Shabani, J Venturini, C Ottanelli… - Cancers, 2022 - mdpi.com
Simple Summary The lung cancer treatment paradigm has been completely changed by
immunotherapy; however, less than half of the treated patients obtain a response, and an …

[PDF][PDF] Tumor immunology and immune checkpoint inhibitors in non-small cell lung cancer

CY Jung, SJ Antonia - Tuberculosis and respiratory …, 2018 - synapse.koreamed.org
Lung cancer is one of the most commonly diagnosed cancers and the leading cause of
cancer-related deaths worldwide. Although progress in the treatment of advanced non-small …

Immunotherapy: from advanced NSCLC to early stages, an evolving concept

T Berghmans, V Durieux, LEL Hendriks… - Frontiers in …, 2020 - frontiersin.org
Immunotherapy in lung cancer treatment is a long history paved with failures and some
successes. During the last decade, the discovery of checkpoints inhibitors led to major …

The cutting-edge progress of immune-checkpoint blockade in lung cancer

F Zhou, M Qiao, C Zhou - Cellular & molecular immunology, 2021 - nature.com
Great advances in immune checkpoint blockade have resulted in a paradigm shift in patients
with lung cancer. Immune-checkpoint inhibitor (ICI) treatment, either as monotherapy or …

Managing resistance to immune checkpoint inhibitors in lung cancer: treatment and novel strategies

A Passaro, J Brahmer, S Antonia, T Mok… - Journal of Clinical …, 2022 - ascopubs.org
A proportion of patients with lung cancer experience long-term clinical benefit with immune
checkpoint inhibitors (ICIs). However, most patients develop disease progression during …