摘要背景性激素与糖尿病的发生具有相关性. 然而, 目前尚未明确性激素途径(sex hormone
pathways, SHPs) 的遗传变异是否有导致2 型糖尿病的风险. 这项研究在参与妇女健康倡议 …

We evaluated associations of insulin sensitivity, metabolic syndrome, and diabetes mellitus
with single nucleotide polymorphism (SNP) variants from sex hormone biosynthesis and …

South Asian women are at increased risk of developing gestational diabetes mellitus (GDM).
Few studies have investigated the genetic contributions to GDM risk. We investigated the …

摘要目前在评估2 型糖尿病的临床以及病理生理发展过程时, 有关性类固醇轴的关键作用往往被
低估了, 特别是许多与心脏代谢结果相关的性别特异性的关系. 在本期Journal of Diabetes …

We synthesized findings relating health outcomes and genetic variants of the sex steroid
hormone pathway in women from the Study of Women's Health Across the Nation (SWAN) …

Context: Steroid sex hormones and SHBG may modify metabolism and diabetes risk, with
implications for sex-specific diabetes risk and effects of prevention interventions. Objective …

To the Editor: Type 2 diabetes (T2D) is one of the most common and fastest growing non-
communicable diseases worldwide. Sex hormone-binding globulin (SHBG) is a circulating …

There is growing evidence that sex and gender differences play an important role in risk and
pathophysiology of type 2 diabetes (T2D). Men develop T2D earlier than women, even …

ContextInconsistent data suggest that endogenous sex hormones may have a role in sex-
dependent etiologies of type 2 diabetes, such that hyperandrogenism may increase risk in …

Background Circulating sex hormone–binding globulin levels are inversely associated with
insulin resistance, but whether these levels can predict the risk of developing type 2 …