海马中的tau-突触长期抑郁相互作用是否在阿尔茨海默病的进展中起关键作用?
Z Hu, T Ondrejcak, P Yu, Y Zhang, Y Yang… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
Cognitive decline in Alzheimer's disease correlates with the extent of tau pathology, in
particular tau hyperphosphorylation that initially appears in the transentorhinal and related …
particular tau hyperphosphorylation that initially appears in the transentorhinal and related …
[HTML][HTML] Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease?
Z Hu, T Ondrejcak, P Yu, Y Zhang, Y Yang… - Neural Regeneration …, 2023 - journals.lww.com
Cognitive decline in Alzheimer's disease correlates with the extent of tau pathology, in
particular tau hyperphosphorylation that initially appears in the transentorhinal and related …
particular tau hyperphosphorylation that initially appears in the transentorhinal and related …
[HTML][HTML] Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model
S Mondragón-Rodríguez, A Salas-Gallardo… - Journal of Biological …, 2018 - ASBMB
Tau hyperphosphorylation at several sites, including those close to the microtubule domain
region (MDr), is considered a key pathological event in the development of Alzheimer's …
region (MDr), is considered a key pathological event in the development of Alzheimer's …
[HTML][HTML] Long-term depression-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats
Y Zhang, Y Yang, Z Hu, M Zhu, S Qin… - Journal of …, 2022 - content.iospress.com
Background: Cognitive decline in Alzheimer's disease (AD) correlates with the extent of tau
pathology, in particular tau hyperphosphorylation, which is strongly age-associated …
pathology, in particular tau hyperphosphorylation, which is strongly age-associated …
Tau protein is required for amyloid β-induced impairment of hippocampal long-term potentiation
OA Shipton, JR Leitz, J Dworzak… - Journal of …, 2011 - Soc Neuroscience
Amyloid β (Aβ) and tau protein are both implicated in memory impairment, mild cognitive
impairment (MCI), and early Alzheimer's disease (AD), but whether and how they interact is …
impairment (MCI), and early Alzheimer's disease (AD), but whether and how they interact is …
Significance of tau in the development of Alzheimer's disease
A Takashima - Brain and nerve= Shinkei kenkyu no shinpo, 2010 - europepmc.org
Based on the amyloid hypothesis, studies on for Alzheimer disease (AD) therapy mostly
focus on elimination of beta-amyloid. However, results of recent studies on amyloid …
focus on elimination of beta-amyloid. However, results of recent studies on amyloid …
[HTML][HTML] The role of pathological tau in synaptic dysfunction in Alzheimer's diseases
M Wu, M Zhang, X Yin, K Chen, Z Hu, Q Zhou… - Translational …, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau …
cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau …
Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion
Tau has been implicated in the organization, stabilization, and dynamics of microtubules. In
Alzheimer's disease and more than 20 neurologic disorders tau missorting …
Alzheimer's disease and more than 20 neurologic disorders tau missorting …
LTD-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats
Y Zhang, Y Yang, Z Hu, M Zhu, S Qin, P Yu, B Li, J Xu… - bioRxiv, 2022 - biorxiv.org
The progressive cognitive decline in Alzheimer's disease (AD) patients correlates with the
extent of tau pathology, in particular tau hyperphosphorylation, which is strongly age …
extent of tau pathology, in particular tau hyperphosphorylation, which is strongly age …
Characterization of a new animal model of Alzheimer's disease: relevance of Tau phosphorylation in hippocampal interneurons
E Dávila Bouziguet - 2022 - diposit.ub.edu
[eng] The neuropathological hallmarks of Alzheimer's disease are senile plaques,
extracellular deposits of amyloid-β peptide (Aβ), and neurofibrillary tangles, intracellular …
extracellular deposits of amyloid-β peptide (Aβ), and neurofibrillary tangles, intracellular …