前列腺素受体配体, 脂肪酸衍生物和相关酶抑制剂对神经轴突细胞的损伤/保护

NA Sharif - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Cellular and mitochondrial membrane phospholipids provide the substrate for synthesis and
release of prostaglandins in response to certain chemical, mechanical, noxious and other …

Neuroaxonal and cellular damage/protection by prostanoid receptor ligands, fatty acid derivatives and associated enzyme inhibitors

NA Sharif - Neural Regeneration Research, 2023 - journals.lww.com
Cellular and mitochondrial membrane phospholipids provide the substrate for synthesis and
release of prostaglandins in response to certain chemical, mechanical, noxious and other …

Neuroprotective effects of prostaglandin analogues on retinal ganglion cell death independent of intraocular pressure reduction

R Yamagishi, M Aihara, M Araie - Experimental eye research, 2011 - Elsevier
Prostaglandin (PG) analogues may have an additional effect to protect neurons independent
of IOP reduction. Only a few reports indicated that some PG analogues had neuroprotective …

[PDF][PDF] Prostaglandins and neural functions: A review

YW Chung-Davidson, K Li, W Li - Adv. Med. Biol., 2013 - novapublishers.com
Prostaglandins are a group of 20-carbon fatty acids produced from arachidonic acid via the
cyclooxygenase (COX) pathway in response to extrinsic stimuli. These fatty acids act …

Latanoprost exerts neuroprotective activity in vitro and in vivo

F Drago, S Valzelli, I Emmi, A Marino, CC Scalia… - Experimental eye …, 2001 - Elsevier
Prostaglandins may influence cyclo-oxygenase (COX-2) and nitric oxide (NO) synthase
activity, thus interfering with ischemia-induced neurotoxic processes. The prostaglandin …

In vitro Effects of Prostaglandin Analogs on Cultured Astrocytes Obtained from the Lamina Cribrosa

JA Shin, NW Kim, SS Kang, ML Kim… - Current Eye …, 2016 - Taylor & Francis
Purpose: To evaluate the effects of prostaglandin analogs (PGAs) on cell viability and
apoptosis in cultured astrocytes obtained from the lamina cribrosa (LC) of the human optic …

Arachidonic acid mediators and their role in neurological disease

M Hoxha - CNS & Neurological Disorders-Drug Targets …, 2022 - ingentaconnect.com
Arachidonic acid (AA)(5, 8, 11, 14-eicosatetraenoic acid) is a polyunsaturated fatty acid,
abundant in cell membrane phospholipids and mainly released upon activation of cytosolic …

Ocular treatments targeting separate prostaglandin receptors in mice exhibit alterations in intraocular pressure and optic nerve lipidome

J Arcuri, A Elbaz, NA Sharif… - Journal of Ocular …, 2023 - liebertpub.com
Background: Prostaglandin (PG) receptor agonists are the first-line eyedrop medication
treatment for glaucoma. The pathophysiology of this disease is not completely known, and …

Prostanoids and their role in cell-cell interactions in the central nervous system

NC Schaad, PJ Magistretti, M Schorderet - Neurochemistry international, 1991 - Elsevier
Although the presence of prostaglandin PGF 2α has been demonstrated in the central
nervous system in the mid sixties, it has taken a rather long time to pinpoint a role of certain …

Positive and negative effects of prostaglandins in A lzheimer's disease

MJ Fattahi, A Mirshafiey - Psychiatry and Clinical …, 2014 - Wiley Online Library
The aim of this review was to clarify the role of prostaglandins and prostaglandin receptors
in the immunopathology of A lzheimer's disease. AP ub M ed search was done using the key …