The recent identification of an intragenic differentially methylated region (DMR) within the
last exon of the bovine Insulin-like growth factor 2 (IGF2) gene provides a diagnostic tool for …

A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent
asymmetry of DNA cytosine methylation (5mC) of alleles at CpG islands (CGIs) in their …

Previous studies revealed that Igf2 and Mpr/Igf2r are imprinted in eutherian mammals and
marsupials but not in monotremes or birds. Igf2 lies in a large imprinted cluster in eutherians …

Imprinting within domains occurs through epigenetic alterations to imprinting centers (ICs)
that result in the establishment of parental-specific differences in gene expression. One …

Monoallelically expressed genes that exert their phenotypic effect in a parent-of-origin
specific manner are considered to be subject to genomic imprinting, the most well …

Genomic imprinting plays a very important role during development and its abnormality may
heavily undermine the developmental potential of bovine embryos. Because of limited …

Imprinted genes play important roles in embryo survival and postnatal growth regulation.
The DLK1 and MEG3 (previously GTL2) genes are linked and reciprocally imprinted in …

Imprinted genes undergo epigenetic modifications during gametogenesis, which lead to
transcriptional silencing of either the maternally or the paternally derived allele in the …

Genomic imprinting is a parent of origin-dependent gene Silencing that involves marking of
alleles in the germline and differential expression in Somatic cells of the offspring. Imprinted …

Background Genomic imprinting affects gene expression in a parent-of-origin manner and
has a profound impact on complex traits including growth and behavior. While the rat is …