[PDF][PDF] Development of DNA vaccine-based anti-tumor immunotherapeutic system
X Guan - 2010 - repository.kulib.kyoto-u.ac.jp
(論文内容の要旨) 抗原特異的な免疫応答を誘導する免疫療法は, 癌や感染症などの様々な難治性
疾患に対する次世代型治療法として期待されている. 抗原タンパク質を遺伝子の形で投与する DNA …
疾患に対する次世代型治療法として期待されている. 抗原タンパク質を遺伝子の形で投与する DNA …
Modulatory effects of tumor-derived heat shock protein in DNA vaccination against nasopharyngeal carcinoma
JJ Wang, C Luo, YH Li, GC Li - International immunopharmacology, 2011 - Elsevier
Use of anti-idiotype antibody vaccines is a promising strategy against tumor, however, their
immunogenicity still need to be improved. Heat shock proteins (HSPs) have been shown to …
immunogenicity still need to be improved. Heat shock proteins (HSPs) have been shown to …
Study on the anti-tumor immune efficacy of tumor-derived heat shock protein70
M Fandong, FU Qingguo, G Kejian… - Zhongguo Mian yi xue …, 2003 - europepmc.org
100% mice received HSP70 10# mu# g immunization survived over 90 days and the
implanted tumors were eradicated. The mice vaccinated with 5# mu# g HSP70 survived for …
implanted tumors were eradicated. The mice vaccinated with 5# mu# g HSP70 survived for …
Specific antitumor immune response induced by pcDNA3. 1/MAGE--3--HSP70 fusion DNA vaccine
L Xinge, S Xiaodong, W Jinmin - Zhonghua wei Sheng wu xue he …, 2005 - europepmc.org
To construct pcDNA3. 1/MAGE-3-HSP70 eukaryotic expression plasmids and to investigate
the capability of pcDNA3. 1/MAGE-3-HSP70 DNA vaccine to induce specific antitumor …
the capability of pcDNA3. 1/MAGE-3-HSP70 DNA vaccine to induce specific antitumor …
[HTML][HTML] Antitumor immunity induced by DNA vaccine encoding alpha-fetoprotein/heat shock protein 70
XP Wang, GZ Liu, AL Song, HY Li… - World Journal of …, 2004 - ncbi.nlm.nih.gov
AIM: To construct a DNA vaccine encoding human alpha-fetoprotein (hAFP)/heat shock
protein 70 (HSP70), and to study its ability to induce specific CTL response and its protective …
protein 70 (HSP70), and to study its ability to induce specific CTL response and its protective …
[PDF][PDF] Autologous Hsp70 immunization induces anti-tumor immunity and increases longevity and survival of tumor-bearing mice
It has been observed that autologous Hsp70 induces specific antitumor immunity and
effectively eradicates tumors in the host mice, thereby enhancing survival of tumorbearing …
effectively eradicates tumors in the host mice, thereby enhancing survival of tumorbearing …
[引用][C] Center for Cell and Gene Therapy [XFH, WR, LR, PP, MS, LS, QG, RS, SY. C.], Department of Molecular and Human Genetics [WR, LR, PP, MS, LS, QG, RS, SY …
PHSPM Oncolytic, XF Huang, W Ren, L Rollins… - Cancer …, 2003 - Waverly Press
Antitumor effect of DC vaccine modified by Hsp70-H22 tumor peptide complex in vitro and in vivo
B Huang, Z Feng, G Zhang - Chinese Journal of Immunology, 2000 - pesquisa.bvsalud.org
Objective: To study the specific antitumor effect of DC modified by Hsp70 tumor peptide
complexes in vitro and in vivo. Methods: The tumor antigen peptides were acquired from …
complexes in vitro and in vivo. Methods: The tumor antigen peptides were acquired from …
Anti-tumor chimeric DNA vaccines based on the expression of HPV-16 E7/E6 epitope genetically fused with the HSP 70N.
LYJ Li YiJie, CKX Chen KaiXu, ZSZ Zhuang ShuZhen… - 2009 - cabidigitallibrary.org
Objective: DNA vaccines encoding the HPV16 E7 and E6 oncoproteins epitope genetically
fused to the HSP70 N fragments were tested in mice for induction of T cell-mediated …
fused to the HSP70 N fragments were tested in mice for induction of T cell-mediated …