Our previous data demonstrated profound anti-tumor and anti-metastatic effects of p62
(sqstm1) DNA vaccine in rodents with various types of transplantable tumors. Testing anti …

Objective To study the efficacy and explore the mechanism of the anti-tumor immunity
elicited by heat shock protein 70-peptide complexes (HSP70-PC) derived from tumor cells …

The over expression of epidermal growth factor (EGF), epidermal growth factor receptor
(EGFR), and vascular endothelial growth factor (VEGF) are observed in several canine …

Objective: To determine the adjuvant activity of recombinant human HSP70D protein.
Methods: Dendritic cells were cultured in vitro, rhHSP70D was added into the culture …

Heat shock proteins (HSP) induce antitumor‐specific immunity via a unique mechanism, but
HSP alone fails to produce a satisfactory antitumor efficacy. We considered that the potent …

Enhancing antitumor immune response by HSPs Page 1 196 Cancer Biology & Therapy 2008;
Vol. 7 Issue 2 Heat-shock proteins (HSPs) are essential to the survival of cells under …

Objective To develop a new vaccine expressing membrane-bound heat shock protein 70
(mbHSP70) and further study its antitumor therapeutic effect. Method The pre-established …

Background The immune factors heat shock protein (HSP)/peptides (HSP/Ps) can induce
both adaptive and innate immune responses. Treatment with HSP/Ps in cancer cell-bearing …

DNA vaccination with the plasmid expressing Japanese encephalitis virus (JEV)
nonstructural protein 1 (pJNS1) has been shown to induce effective immunity against JEV …