抄録 Adjuvant-free vaccination with tumor-derived heat shock protein (HSP)-peptide
complex has been previously shown to elicit tumor-specific protective and therapeutic …

Dendritic cells were cultured in vitro, rhHSP70D was added into the culture medium, the
cytokine secretion and maturation of dendritic cells (DC) stimulated by rhHSP70D were …

Heat Shock protein-70 derived from tumor cells is highly immunogenic and induces specific
anti-tumor immune response by directly activating cytotoxic CD8+ T cells. Additionally …

Mice immunized with HSP70-associated peptide complexes were protected from HCaF
challenge. The immunoprotective effect in female mice was better than the male groups …

Methods TRP2 (153-243) and Hsp70L1 genes were obtained by RT-PCR from B16 cells in
murine melanoma and from spleens of C57BL/6 mice and then were inserted into pcDNA3 …

Our previous data demonstrated profound anti-tumor and anti-metastatic effects of p62
(sqstm1) DNA vaccine in rodents with various types of transplantable tumors. Testing anti …

Induction of tumor necrosis factor in sera (TNS) as a multidisciplinary cancer therapy by the
administration of a combination of 2-carboxyethylgermanium sesquioxide (Ge-132) and …

Abstract Interleukin-12 (IL-12), a proinflammatory cytokine, shows anticancer properties.
Systemically administered IL-12 causes dose-dependent toxicity. To achieve localized …

Introduction: Lymphoma is one of the most common cancers in dogs and while clinical
remission can be induced using chemotherapy, very few dogs are cured. Since cytokine …

Abstract 1883 The purpose of the present study was to 1) assess the safety and tolerability of
the ImmuneFx cancer vaccine in canine lymphosarcoma, a well-accepted model for Non …