Identifying gene variants causing monogenic diabetes (MD) increases understanding of
disease etiology and allows for implementation of precision therapy to improve metabolic …

Background Diagnosis of monogenic as well as atypical forms of diabetes mellitus has
important clinical implications for their specific diagnosis, prognosis, and targeted treatment …

The precision medicine approach of tailoring treatment to the individual characteristics of
each patient or subgroup has been a great success in monogenic diabetes subtypes, MODY …

Monogenic forms of diabetes present opportunities for precision medicine as identification of
the underlying genetic cause has implications for treatment and prognosis. However …

Introduction Monogenic diabetes is attributed to genetic variations in a single gene. Maturity-
onset diabetes of the young (MODY) is the most common phenotype associated with …

Aims Diabetes is increasing globally and Asia is the epicenter. Among those with young-
onset diabetes (< 45 years), the prevalence of monogenic diabetes is estimated to be non …

Aims/hypothesis Current genetic tests for diagnosing monogenic diabetes rely on selection
of the appropriate gene for analysis according to the patient's phenotype. Next-generation …

Type 1 diabetes affects millions of people globally and requires careful management to
avoid serious long-term complications, including heart and kidney disease, stroke, and loss …

Aim Monogenic diabetes (MD) represents 5–7% of antibody-negative diabetes cases and is
a heterogeneous group of disorders. Methods We used targeted next-generation …

After many years of effort with only modest result, the last 5 years has seen a tremendous
surge in our understanding of the genetics of diabetes. This review will focus on the …