Immunotherapy with DCs as antigen-presenting vehicles have already improved patients'
outcome against a variety of tumors. Moreover, MSCs were recently used to develop anti …

Repetitive vaccinations with dendritic cell (DC)-based vaccines over long periods of time
can break pre-existing tolerance to tumors and achieve clinically relevant immune response …

DNA vaccination is a simple and effective method to induce immune responses against a
variety of tumors as well as infectious diseases. Vaccination with major histocompatibility …

Background DNA vaccines have been shown to be an effective approach to induce antigen‐
specific cellular and humoral immunity. However, the lower immune intensity in clinical trials …

Dendritic cells (DCs) have been used in a number of clinical trials for cancer
immunotherapy; however, they have achieved limited success in solid tumors. Consequently …

Tumor cells express tumor‐associated antigens (TAAs), which can serve as targets for the
immune system. However, the majority of TAAs are overexpressed products of normal …

Vaccination of mice with heat shock proteins (HSPs) derived from a tumor makes the mice
resistant to the tumor from which the HSP was obtained. This phenomenon has been …

Tumor-derived heat shock proteins have been shown previously to elicit specific
prophylactic immunity to cognate tumors. Here we establish that administration of gp96 …

Hepatocellular carcinoma (HCC) is one of the most common malignancies over the world.
Alpha-fetoprotein (AFP) is an oncofetal protein during HCC development, which could …

A novel membrane-bound heat shock protein 70 (mbHSP70) was expressed on the surface
of the mouse mastocytoma cell line P815 to enhance immunogenicity of tumor cells. The in …