It is suggested that cholesterol efflux mediated by ATP binding cassette transporter A1
(ABCA1) plays an important role in anti‐atherogenesis. However, the effects of inflammatory …

ATP-binding cassette transporter A1 (ABCA1) as one kind of membrane protein was found
recently to play a major role in cholesterol homeostasis. Angiotensin II (AngII) has been …

To study the effect of oleate on ATP binding cassette transporter A1 (ABCA1) expression
and cholesterol efflux in THP-1 macrophage-derived foam cells, after exposure of the …

Background: Interleukin (IL)-18 and IL-12 synergize for the production of interferon (IFN)-γ,
which can downregulate ATP-binding cassette transporter A1 (ABCA1) expression. The aim …

The ATP-binding-cassette transporter A1 (ABCA1) plays an essential role in cellular
cholesterol efflux and helps prevent macrophages from becoming foam cells. The statins are …

Cholesterol-loaded macrophage foam cells are a central component of atherosclerotic
lesions. ATP binding cassette transporter A1 (ABCA1), the defective molecule in Tangier …

ATP-binding cassette transporter A1 (ABCA1), a pivotal regulator of cholesterol efflux from
cells to apolipoproteins, plays an important role in cholesterol homeostasis. As an …

Abstract Interleukin-5 (IL-5) is manifested as its involvement in the process of
atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL …

Background—Patients with type 2 diabetes mellitus are at increased risk for the
development of atherosclerosis. A pivotal event in the development of atherosclerosis is …

Background—Accumulation of excess cholesterol by intimal arterial smooth muscle cells
(SMCs) contributes to the formation of foam cells in atherosclerotic lesions. The purpose of …