Differential DNA methylation and network analysis in schizophrenia

HK Chuan - Computational epigenetics and diseases, 2019 - Elsevier
Schizophrenia is a multidimensional disorder, where a network analysis may be necessary
to create a better understanding on its etiology. Methods for DNA methylation of …

[HTML][HTML] Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia

SA Lee, KC Huang - BMC medical genomics, 2016 - Springer
Background Epigenetics of schizophrenia provides important information on how the
environmental factors affect the genetic architecture of the disease. DNA methylation plays a …

Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods

BT Moghadam, M Etemadikhah, G Rajkowska… - Journal of psychiatric …, 2019 - Elsevier
Schizophrenia is a common mental disorder with high heritability. It is genetically complex
and to date more than a hundred risk loci have been identified. Association of environmental …

Machine learning based classification of mental disorders from methylation data

C Bartlett, I Bichindaritz - Innovation in Medicine and Healthcare Systems …, 2019 - Springer
Psychiatric disorder diagnoses are heavily reliant on the Diagnostic and Statistical Manual
of Mental Disorders' listing of observable symptoms and clinical traits, the skill level of the …

Machine learning and feature selection for the classification of mental disorders from methylation data

CL Bartlett, SJ Glatt, I Bichindaritz - … , AIME 2019, Poznan, Poland, June 26 …, 2019 - Springer
Psychiatric disorder diagnoses are heavily reliant on observable symptoms and clinical
traits, the skill level of the physician, and the patient's ability to verbalize experienced events …

[HTML][HTML] DNA methylation in schizophrenia: progress and challenges of epigenetic studies

M Nishioka, M Bundo, K Kasai, K Iwamoto - Genome medicine, 2012 - Springer
Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …

A novel schizophrenia diagnostic model based on statistically significant changes in gene methylation in specific brain regions

D Zou, Y Qiu, R Li, Y Meng, Y Wu - BioMed Research …, 2020 - Wiley Online Library
Objective. The present study identified methylation patterns of schizophrenia‐(SCZ‐) related
genes in different brain regions and used them to construct a novel DNA methylation‐based …

Genome-wide methylation profiling of schizophrenia

B Rukova, R Staneva, S Hadjidekova… - Balkan Journal of …, 2014 - sciendo.com
Schizophrenia is one of the major psychiatric disorders. It is a disorder of complex
inheritance, involving both heritable and environmental factors. DNA methylation is an …

[HTML][HTML] DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks

CA Castellani, BI Laufer, MG Melka, EJ Diehl… - BMC medical …, 2015 - Springer
Background Despite their singular origin, monozygotic twin pairs often display discordance
for complex disorders including schizophrenia. It is a common (1%) and often familial …

Classification of schizophrenia by iterative random forest feature selection based on DNA methylation array data

X Hu, M Li, L Wang, X Li, FX Wu… - 2019 IEEE International …, 2019 - ieeexplore.ieee.org
Changes in DNA methylation are widely thought to be involved in the evolution of the
disease, and most studies suggest that whole genome hypo-methylation levels are …