Gliomas are the most common intracranial tumors. In the US, approximately 15,000 patients
die with glioblastoma per year (CBTRUS 2002). Despite modern diagnostics and treatments …

Glioblastoma multiforme is the most common and lethal primary malignant brain tumor.
Although considerable progress has been made in technical proficiencies of surgical and …

The current understanding of glioma biology reveals targets for anti-invasive therapy which
include manipulations of extracellular matrix and receptors, growth factors and cytokines …

Gliomas are the most common intracranial tumors in humans. The most malignant among
these tumors is glioblastoma (GBM), with an incidence of 3–5 out of 100,000 persons in …

Although significant technical advances in surgical and radiation treatment for brain tumors
have emerged in recent years, their impact on clinical outcome for patients has been …

Tumors of glial origin consist of a core mass and a penumbra of invasive, single cells,
decreasing in numbers towards the periphery and still detectable several centimeters away …

Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …

Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy
in adults. Despite the advances made in surgical techniques, radiotherapy and …

Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …

Purpose The present review aims to emphasize that malignant gliomas are characterized by
the diffuse invasion of distant brain tissue by a myriad of single migrating cells that exhibit …