[HTML][HTML] Septin 4 activates PPARγ/LXRα signaling by upregulating ABCA1 and ABCG1 expression to inhibit the formation of THP‑1 macrophage‑derived foam cells

X Song, G Yan, H Wang, D Lou - Experimental and …, 2021 - spandidos-publications.com
Septin 4 is a member of a family of GTP‑binding proteins that has been previously reported
regulate cytoskeletal organization. In addition, it has been suggested to serve a role in …

Visfatin promotes foam cell formation by dysregulating CD36, SRA, ABCA1, and ABCG1 expression in RAW264. 7 macrophages

YT Lin, DY Jian, CF Kwok, LT Ho, CC Juan - Shock, 2016 - journals.lww.com
Background: Visfatin is produced in and secreted from adipocytes. Increased circulating
visfatin level is observed in obese subjects. Previous studies demonstrated that visfatin was …

[HTML][HTML] Lowering the n-6/n-3 PUFAs ratio inhibits the formation of THP-1 macrophage-derived foam cell

Z Song, H Xia, L Yang, S Wang, G Sun - Lipids in health and disease, 2018 - Springer
Background The balance between n-6 and n-3 PUFAs is an important determinant in the risk
for cardiovascular disease. The study was to investigate the influence of the n-6 and n-3 …

[HTML][HTML] Allicin induces the upregulation of ABCA1 expression via PPARγ/LXRα signaling in THP-1 macrophage-derived foam cells

XL Lin, HJ Hu, YB Liu, XM Hu… - International …, 2017 - spandidos-publications.com
Allicin is considered anti-atherosclerotic due to its antioxidant and anti-inflammatory effects,
which makes it an important drug for the prevention and treatment of atherosclerosis …

Expression of Septin4 in human hepatic stellate cells LX-2 stimulated by LPS

X Sun, Y Yang, D Zhu, H Qian, Y Duan, X He, X Gu… - Inflammation, 2013 - Springer
Septin4, a member of polymerizing GTP-binding proteins family, is reported to be involved in
cytoskeletal organization in mitosis, apoptosis, fibrosis, and other cellular processes. Since …

[HTML][HTML] The cytoskeletal protein septin 11 is associated with human obesity and is involved in adipocyte lipid storage and metabolism

N Moreno-Castellanos, A Rodríguez, Y Rabanal-Ruiz… - Diabetologia, 2017 - Springer
Aims/hypothesis Septins are newly identified members of the cytoskeleton that have been
proposed as biomarkers of a number of diseases. However, septins have not been …

Pentraxin 3 promotes oxLDL uptake and inhibits cholesterol efflux from macrophage-derived foam cells

W Liu, J Jiang, D Yan, D Li, W Li, Y Ma, L Yang… - Experimental and …, 2014 - Elsevier
Background The objective of this study was to determine the effects of pentraxin3 (PTX3) on
human oxidized low density lipoprotein (oxLDL) uptake and cholesterol efflux from human …

[HTML][HTML] Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1

S Zhuo, S Song, C Wang, Z Wang, M Zhang, D Lin… - Scientific Reports, 2024 - nature.com
The inflammatory corpuscle recombinant absents in melanoma 2 (AIM2) and cholesterol
efflux protein ATP binding cassette transporter A1 (ABCA1) have been reported to play …

Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation

EW Huang, CZ Liu, SJ Liang, Z Zhang, XF Lv, J Liu… - Atherosclerosis, 2016 - Elsevier
Background and aims Macrophage-derived foam cell formation (MFCF) is a crucial step in
the pathogenesis of atherosclerosis. Uptake of oxidized low-density lipoprotein (oxLDL) by …

Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation

F Zhang, X Xia, R Chai, R Xu, Q Xu… - Journal of Cellular …, 2020 - Wiley Online Library
Atherosclerosis is regarded as a chronic progressive inflammatory disease and is a basic
pathophysiological process in coronary artery disease which is life threatening in clinic. The …