[PDF][PDF] 肿瘤突变负荷与肿瘤浸润性免疫细胞在结直肠癌预后及进展中的作用
时姗姗， 李霄， 丁颖， 宋国新， 张智弘 - 临床与病理杂志, 2022 - cdn.amegroups.cn
目的: 本文旨在通过分析结直肠癌(colorectal cancer, CRC) 中肿瘤突变负荷(tumor mutational
burden, TMB), 肿瘤浸润性免疫细胞(tumor-infiltrating immune cells, TICs) …
burden, TMB), 肿瘤浸润性免疫细胞(tumor-infiltrating immune cells, TICs) …
Correlations between tumor mutation burden and immunocyte infiltration and their prognostic value in colon cancer
Z Zhou, X Xie, X Wang, X Zhang, W Li, T Sun… - Frontiers in …, 2021 - frontiersin.org
Background Colon cancer has a huge incidence and mortality worldwide every year.
Immunotherapy could be a new therapeutic option for patients with advanced colon cancer …
Immunotherapy could be a new therapeutic option for patients with advanced colon cancer …
Exploration of the role of tumor mutation burden in clinical significance, immunotherapy response predictor and immune cell infiltration in colon cancer
Z Xu, C Qu, J Guo, X Li, Y Wu, K Wang, J Zheng, X Sun… - 2020 - researchsquare.com
Methods: The transcriptome profiling data of colon patients and the simple nucleotide
variation data of colon cases were downloaded from the Cancer Genome Atlas (TCGA) …
variation data of colon cases were downloaded from the Cancer Genome Atlas (TCGA) …
[HTML][HTML] Exploration of the relationship between tumor mutation burden and immune infiltrates in colon adenocarcinoma
R Ouyang, Z Li, P Peng, J Zhang, J Liu… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Background: Tumor mutation burden (TMB) was correlated with the immunotherapeutic
response in various malignancies. We aimed to evaluate the TMB immune signature in …
response in various malignancies. We aimed to evaluate the TMB immune signature in …
Influence of Tumor Mutational Burden on Immune-infiltrating Cells in Stomach Adenocarcinoma
Z Zhao, S Li, S Li, H Yang, D Wang, W Fu - 2020 - researchsquare.com
Background: Gastric cancer (GC) is one of the most common and fatal cancers worldwide.
Tumor mutational burden (TMB) is described as a novel powerful signature to predict …
Tumor mutational burden (TMB) is described as a novel powerful signature to predict …
Clinical relevance of intra-tumoral density of regulatory T cells as a predictive factor for chemotherapy response in metastatic colorectal cancer
Background: Within the tumor microenvironment, regulatory T cells (Tregs) are potent
facilitators of immune tolerance, and in most solid tumors a higher proportion of Tregs …
facilitators of immune tolerance, and in most solid tumors a higher proportion of Tregs …
结直肠癌及腺瘤患者CD4+, CD8+ 和CD28+ T 淋巴细胞的亚群变化及临床意义
张泉， 邱思芳， 赵逵 - 中国癌症杂志, 2018 - china-oncology.com
背景与目的: 结直肠癌(colorectal cancer, CRC) 严重影响患者生存. 探讨肿瘤微环境(tumor
microenvironment, TME) T 细胞亚群在CRC 和腺瘤中的表达及意义. 方法 …
microenvironment, TME) T 细胞亚群在CRC 和腺瘤中的表达及意义. 方法 …
Transcriptomic Analysis of Metastatic Colorectal Tumor with Low Mutational Burden
K Wang, S Mu - Proceedings of Anticancer Research, 2024 - ojs.bbwpublisher.com
Objective: To identify potential drug targets for metastasis colorectal cancer (CRC) patients
with low mutational burden by examining differences in immune-related gene expression …
with low mutational burden by examining differences in immune-related gene expression …
肿瘤负荷对大肠癌患者外周血T 细胞分化的影响
崔明， 王杉， 叶颖江， 崔志荣， 柯杨 - 中华医学杂志, 2007 - cqvip.com
目的探讨肿瘤负荷对于大肠癌患者外周血T1 (分泌Ⅰ 类因子T 细胞), T2 (分泌Ⅱ 类因子T 细胞)
分化的影响及其临床意义. 方法连续采集20 例大肠癌患者(17 例行根治术, 3 例行姑息切除术) …
分化的影响及其临床意义. 方法连续采集20 例大肠癌患者(17 例行根治术, 3 例行姑息切除术) …
[HTML][HTML] TCGA database analysis of the tumor mutation burden and its clinical significance in colon cancer
J Chen, A Apizi, L Wang, G Wu, Z Zhu… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background Colon cancer is one of the most common malignant tumors, with high rates of
incidence and death. The tumor mutational burden (TMB), which is characterized by …
incidence and death. The tumor mutational burden (TMB), which is characterized by …