Estrogen signaling exerts a decisive role in female sex determination and differentiation in
chicken and fish. Aromatase encoded by Cyp19a1 is the key enzyme that catalyzes the …

Embryonic gonad sex in many reptilian species is determined by the incubation temperature
of the egg, a differentiation process known as temperature-dependent sex determination …

In the red-eared slider turtle (Trachemys scripta), a species with temperature-dependent sex
determination (TSD), the expression of the aromatase gene during gonad development is …

The molecular mechanisms underpinning temperaturedependent sex determination (TSD)
in reptiles have attracted great biological interest for many years. However, which genetic …

The developmental processes underlying gonadal differentiation are conserved across
vertebrates, but the triggers initiating these trajectories are extremely variable. The red …

It has been demonstrated that estrogens are indispensable for male fertility in mammals.
Aromatase (encoded by CYP19) catalyzes the final step of estradiol biosynthesis. However …

Simple Summary The mechanism of sex determination and differentiation in animals has
remained a central focus of reproductive and developmental biology research. Among …

Although the role of aromatase in many estrogen-dependent reproductive and metabolic
functions is well documented in vertebrates, its involvement in the ovarian development of …

The Chinese soft-shelled turtle (Pelodiscus sinensis) is an important aquaculture animal in
China and exhibits growth dimorphism. Single-male cultures are often selected for higher …

Aromatase (encoded by the cyp19a1a and cyp19a1b genes) plays a central role in sex
differentiation in fish, but its precise roles during sex differentiation are still largely unknown …