Minocycline 對於大鼠視網膜缺血再灌流性傷害的神經保護效力

黃珮筠 - 2008 - tdr.lib.ntu.edu.tw
美諾四環黴素(minocycline) 是一種半合成, 四環素(tetracycline) 的第二代衍生物,
應用於治療格蘭氏陰性菌或陽性菌的感染, 近年來在許多研究腦部缺血或退化性疾病的實驗模式 …

MINOCYCLINE HAS A NEUROPROTEC-TIVE EFFECT ON RETINAL GANGLION CELLS SURVIVAL AFTER OPTIC NERVE TRANSECTION IN RATS

H Levkovitch-Verbin, G Treister, Z Vilner, S Melamed - 国际眼科杂志, 2003 - cqvip.com
Purpose: To evaluate the neuroprotective effect of Minocycline on retinal ganglion cells
(RGCs) survival after optic nerve tran-section in rats. Minocycline is commonly used by …

局部抗青光眼藥, 全身性神經保護藥物與抗氧化營養添加物對高眼壓傷害之大鼠視網膜的保護效力研究

陳以瑛 - 臺灣大學臨床動物醫學研究所學位論文, 2012 - airitilibrary.com
青光眼是一個多因子的疾病, 病變特徵為漸進性視網膜及視神經退化, 為造成永久性失明的第二
大主因. 青光眼的起始及進展都與視網膜缺血病變有關, 因此本試驗以高眼壓誘導視網膜缺血之 …

Neuroprotective effects of minocycline on retinal ganglion cells in early stage of optic nerve crush injury

J Xiaoling, P Yuan, Y Liu - Chinese Journal of Experimental …, 2014 - pesquisa.bvsalud.org
Background Minocycline possesses neuroprotective effect in a variety of animal models and
clinical trials of central nervous system, but whether it works on optic nerve injury remains …

[HTML][HTML] Neuroprotective effect of minocycline on rat retinal ischemia-reperfusion injury

X Li, Z Ye, S Pei, D Zheng, L Zhu - Molecular Vision, 2021 - ncbi.nlm.nih.gov
Purpose To examine the neuroprotective effect of minocycline on retinal ischemia-
reperfusion (IR) injury in rats and investigate its possible mechanism of action. Methods …

[HTML][HTML] Low-dose minocycline mediated neuroprotection on retinal ischemia-reperfusion injury of mice

R Huang, S Liang, L Fang, M Wu, H Cheng, X Mi… - Molecular …, 2018 - ncbi.nlm.nih.gov
Purpose The aim of this study was to investigate the effect of minocycline (MC) on the
survival of retinal ganglion cells (RGCs) in an ischemic-reperfusion (I/R) injury model of …

Minocycline is Neuroprotective in a Rat Model of Optic Nerve Transection

H Levkovitch-Verbin, Z Vilner… - … & Visual Science, 2003 - iovs.arvojournals.org
Purpose: To evaluate the neuroprotective effect of Minocycline on the survival of retinal
ganglion cells (RGCs) after optic nerve transection in rats. Minocycline is an antimicrobial …

Incomplete protective effects of minocycline on traumatic brain injury in rats and mice

WW Sheng, WP Zhang, ML Wang… - Zhejiang da xue xue …, 2006 - europepmc.org
Objective To evaluate protective effect of minocycline, a semisynthetic tetracycline derivative
on different traumatic brain injuries in rats and mice. Methods The opened brain trauma was …

Minocycline shows promise as safe neuroprotective agent: commonly used drug improves retinal ganglion cell survival in mice with induced glaucoma.

C Guttman - Ophthalmology Times, 2004 - go.gale.com
Dr. Levkovitch-Verbin and colleagues at the Goldschleger Eye Institute, Sheba Medical
Center, Tel Aviv University, Tel Hashomer, Israel, investigated minocycline's activity for …

Lidocaine 與Methylprednisolone 對於大鼠視網膜缺血再灌流病變模式的神經保護效力

蔡文智 - 2006 - airitilibrary.com
本實驗目的為評估注射型藥物 lidocaine (LDC) 與 methylprednisolone (MP)
是否對於視網膜缺血性病變有神經保護效果. 經高眼內壓誘發視網膜缺血, 將 SD 大鼠分成三組 …