[PDF][PDF] 丙酮酸脱氢酶复合体E2 亚基通过活化Toll 样受体4 影响单核细胞分泌细胞因子

杨再兴, 梁艳, 刘东红, 张治宇… - Journal of Wenzhou …, 2017 - xb.wmu.edu.cn
目的: 探讨丙酮酸脱氢酶复合体E2 亚基(PDC-E2) 是否可以活化Toll 样受体4 (TLR4)-NF-κB
通路, 并通过该通路诱导单核细胞分泌肿瘤坏死因子α (TNF-α), 白介素12 (IL-12) …

Rab7 GTPase 负向调节巨噬细胞中poly I: C 诱导的细胞因子的表达

王玉珍, 谢基明, 王宁飞, 刘帅 - 中国免疫学杂志, 2011 - cqvip.com
目的: 通过构建Rab7 的失活突变载体tRab7 (Rab7T22N), 研究Rab7 失活突变后对poly I: C
诱导的RAW264. 7 巨噬细胞中细胞因子的影响. 方法: 利用PCR 定点突变法构建Rab7 …

NF-κB 途径介导Chemerin 抑制THP-1 源性巨噬泡沫细胞ABCAl 表达和降低胆固醇外流

谢霆, 陈新忠, 董念国, 夏东升, 杨文凯… - 华中科技大学学报: 医学 …, 2012 - cqvip.com
目的观察脂肪因子Chemerin 是否调节胆固醇流出和巨噬泡沫细胞脂滴蓄积,
以及对巨噬泡沫细胞ATP 结合盒转运子A1 (ATP-binding cassette transporter A1, ABCA1) …

内毒素介导Kupffer 细胞脂多糖受体CD14 的表达

龚建平, 徐明清, 李昆, 朱瑾, 韩本立 - 第三军医大学学报, 2001 - cqvip.com
目的观察内毒素刺激下肝Kupffer 细胞(KCs) 膜上脂多糖(LPS) 受体CD14
的表达及其在细胞因子分泌中的作用. 方法从Wistar 大鼠肝组织中分离出KCs, 培养12 h …

白细胞介素10 对人THP-1 源巨噬细胞泡沫化过程中SR-A 表达的影响

杨红, 戴亚蕾, 徐婷, 田菲 - 临床心血管病杂志, 2008 - cqvip.com
目的: 本研究旨在观察白细胞介素-10 (IL-10) 对人THP1 源巨噬细胞泡沫化过程中清道夫受体A
(SRA) 表达的影响, 探讨在动脉粥样硬化形成中IL10 对氧化型低密度脂蛋白(ox-LDL) …

[HTML][HTML] Septin 4 activates PPARγ/LXRα signaling by upregulating ABCA1 and ABCG1 expression to inhibit the formation of THP‑1 macrophage‑derived foam cells

X Song, G Yan, H Wang, D Lou - Experimental and …, 2021 - spandidos-publications.com
Septin 4 is a member of a family of GTP‑binding proteins that has been previously reported
regulate cytoskeletal organization. In addition, it has been suggested to serve a role in …

Interleukin-5 promotes ATP-binding cassette transporter A1 expression through miR-211/JAK2/STAT3 pathways in THP-1-dervied macrophages

K Chen, Z Zhao, G Wang, J Zou, X Yu… - Acta Biochimica et …, 2020 - academic.oup.com
Abstract Interleukin-5 (IL-5) is manifested as its involvement in the process of
atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL …

Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cβ/store-operated calcium entry/calreticulin …

Y Li, M Zhou, H Li, C Dai, L Yin, C Liu, Y Li… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Macrophage-derived foam cells play a causal role during the
pathogenesis of atherosclerosis. P2Y6 receptor (P2Y6R) highly expressed has been …

[引用][C] Pannexin1 对LXR 介导的巨噬细胞吞噬ox-LDL 的影响及分子机制的初探

徐丽娜 - 2017 - 大连医科大学

[引用][C] P2x7 receptor inhibitor suppressed extracellular atp/lps-primed human hepatic stellate cells activation via downregulating nlrp3 inflammasome

S Jiang, Q Jin, YL WU, YL Yao, JX Nan, LH Lian - Chin. J. Pharmacol. Toxico, 2015