內分泌系統為無導管腺體, 藉由分泌激素去調控動物體內各種生理功能之正常運作,
是維持體內恆定的重要控制系統. 臨床上常見的內分泌疾病包括糖尿病, 甲狀腺疾病以及肥胖症 …

The rat S14 gene has been a useful model to study carbohydrate and triiodothyronine (T3)
regulation of hepatic gene expression. To gain insight into the regulation and function of the …

Abstract 3T3-F442A cells differentiate from preadipocytes to adipocytes when cultured in
medium containing fetal calf serum and insulin. We examined the regulation of the S14 gene …

S14 is a gene known to be under thyroid hormone control. Its mRNA concentration is very
high in lipogenic tissues, and although the precise function of the protein is still unknown …

Spot 14 (S14) is a protein whose mRNA is rapidly up-regulated by lipogenic stimuli
including thyroid hormone and a high-carbohydrate diet. Previous investigation into the role …

S14 has been identified as a potent stimulator of de novo hepatic lipogenesis (DNL) in
rodents. However, it is unclear how S14 is regulated in humans with non-alcoholic fatty liver …

During adipogenic conversion of 3T3-L1 cells S14-mRNA increased from undetectable
levels in preadipocytes to high levels in differentiated adipocytes (adipocyte-like cells). In …

The rat S14 gene encodes a protein of unknown function and has an amino acid sequence
unrelated to any published sequences. Expression of mRNA S14 and lipogenesis in liver …

The steadily increasing epidemic of obesity continues at alarming rates, is an important
public health problem, and expression changes of S100A16 and 11 β-hydroxysteroid …

Spot 14 (S14) protein is primarily expressed in adipogenic tissues. Compared to wild type,
S14 knockout mice had better resistance to diet-induced obesity and glucose tolerance …