Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1–A2A receptor heteromers
The functional role of heteromers of G-protein-coupled receptors is a matter of debate. In the
present study, we demonstrate that heteromerization of adenosine A 1 receptors (A 1 Rs) …
present study, we demonstrate that heteromerization of adenosine A 1 receptors (A 1 Rs) …
Heterodimeric adenosine receptors: a device to regulate neurotransmitter release
Since 1990 it has been known that dimers are the basic functional form of nearly all G-
protein-coupled receptors (GPCRs) and that homo-and heterodimerization may play a key …
protein-coupled receptors (GPCRs) and that homo-and heterodimerization may play a key …
[PDF][PDF] Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain
[Frontiers in Bioscience 13, 2391-2399, January 1, 2008] 2391 Adenosine A1-A2A receptor
heteromers: new targets for caffeine in Page 1 [Frontiers in Bioscience 13, 2391-2399, January …
heteromers: new targets for caffeine in Page 1 [Frontiers in Bioscience 13, 2391-2399, January …
Anatomy of adenosine A2A receptors in brain: Morphological substrates for integration of striatal function
A2A adenosine receptors (A2ARs) are expressed with the greatest abundance in the
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the …
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the …
Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus
Adenosine is a neuromodulator that controls neurotransmitter release through inhibitory A1
and facilitatory A2A receptors. Although both adenosine receptor-mediated inhibition and …
and facilitatory A2A receptors. Although both adenosine receptor-mediated inhibition and …
A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment
B Johansson, V Georgiev, K Lindström, BB Fredholm - Brain research, 1997 - Elsevier
The effect of oral treatment with caffeine, in doses that are known to produce marked
adaptive effects, was investigated on A1 and A2A receptors in the mouse brain. Caffeine …
adaptive effects, was investigated on A1 and A2A receptors in the mouse brain. Caffeine …
Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson's disease
K Fuxe, LF Agnati, K Jacobsen, J Hillion, M Canals… - Neurology, 2003 - AAN Enterprises
Recently evidence has been presented that adenosine A2A and dopamine D2 receptors
form functional heteromeric receptor complexes as demonstrated in human neuroblastoma …
form functional heteromeric receptor complexes as demonstrated in human neuroblastoma …
Adenosine receptor neurobiology: overview
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the
body as a metabolic intermediary. In the brain, adenosine functions as an important …
body as a metabolic intermediary. In the brain, adenosine functions as an important …
Different synaptic and subsynaptic localization of adenosine A2A receptors in the hippocampus and striatum of the rat
Adenosine A2A receptors are most abundant in the striatum where they control the
striatopallidal pathway thus controlling locomotion. Extra-striatal A2A receptors are …
striatopallidal pathway thus controlling locomotion. Extra-striatal A2A receptors are …
Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
Activation of adenosine A2A receptors (A2AR) has been shown to antagonize the function of
D2 dopaminergic regulation of striatal γ‐aminobutyric acid (GABA)‐ergic output and, thus …
D2 dopaminergic regulation of striatal γ‐aminobutyric acid (GABA)‐ergic output and, thus …