[HTML][HTML] 肌特异性microRNA 作为杜氏肌营养不良生物标志物的研究进展

孟琦, 蓝丹 - Chinese Journal of Contemporary Pediatrics, 2019 - ncbi.nlm.nih.gov
Abstract microRNA( miRNA) 是一种长度约22nt 的非编码单链RNA, 主要在转录后调控基因的
表达。 目前miRNA 已成为多种疾病潜在的生物标志物, 如肿瘤、 白血病、 神经系统疾病等 …

A review on muscle-specific microRNAs as the biomarker for Duchenne muscular dystrophy

Q Meng, D Lan - Zhongguo Dang dai er ke za zhi= Chinese Journal …, 2019 - europepmc.org
Abstract microRNA (miRNA) 是一种长度约 22nt 的非编码单链 RNA, 主要在转录后调控基因的
表达. 目前 miRNA 已成为多种疾病潜在的生物标志物, 如肿瘤, 白血病, 神经系统疾病等 …

[HTML][HTML] Plasma microRNAs as biomarkers for myotonic dystrophy type 1

A Perfetti, S Greco, E Bugiardini, R Cardani… - Neuromuscular …, 2014 - Elsevier
Abstract Myotonic dystrophy type 1 (DM1) lacks non-invasive and easy to measure
biomarkers, still largely relying on semi-quantitative tests for diagnostic and prognostic …

[HTML][HTML] Elevated muscle-specific miRNAs in serum of myotonic dystrophy patients relate to muscle disease progress

A Koutsoulidou, TC Kyriakides, GK Papadimas… - PloS one, 2015 - journals.plos.org
The discovery of reliable and sensitive blood biomarkers is useful for the diagnosis,
monitoring and potential future therapy of diseases. Recently, microRNAs (miRNAs) have …

[HTML][HTML] Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy

H Mizuno, A Nakamura, Y Aoki, N Ito, S Kishi… - PloS one, 2011 - journals.plos.org
Duchenne muscular dystrophy (DMD) is a lethal X-linked disorder caused by mutations in
the dystrophin gene, which encodes a cytoskeletal protein, dystrophin. Creatine kinase (CK) …

[HTML][HTML] Validation of plasma microRNAs as biomarkers for myotonic dystrophy type 1

A Perfetti, S Greco, R Cardani, B Fossati, G Cuomo… - Scientific reports, 2016 - nature.com
Non-invasive and simple to measure biomarkers are still an unmet need for myotonic
dystrophy type 1 (DM1). Indeed, muscle biopsies can be extremely informative, but their …

[HTML][HTML] Circulating muscle-specific miRNAs in Duchenne muscular dystrophy patients

X Li, Y Li, L Zhao, D Zhang, X Yao, H Zhang… - … Therapy-Nucleic Acids, 2014 - cell.com
Noninvasive biomarkers with diagnostic value and prognostic applications have long been
desired to replace muscle biopsy for Duchenne muscular dystrophy (DMD) patients …

[HTML][HTML] Novel miRNA biomarkers for patients with Duchenne muscular dystrophy

Q Meng, J Zhang, J Zhong, D Zeng, D Lan - Frontiers in Neurology, 2022 - frontiersin.org
Creatine kinase (CK) as a biomarker has long been expected to be replaced by other fluid
biomarkers for Duchenne muscular dystrophy (DMD) because it is independent of disease …

[HTML][HTML] The biomarker potential of miRNAs in myotonic dystrophy type I

E Koehorst, A Ballester-Lopez… - Journal of Clinical …, 2020 - mdpi.com
MicroRNAs (miRNAs) are mostly known for their gene regulation properties, but they also
play an important role in intercellular signaling. This means that they can be found in bodily …

Micro-RNA expression in muscle and fiber morphometry in myotonic dystrophy type 1

C Fritegotto, C Ferrati, V Pegoraro, C Angelini - Neurological Sciences, 2017 - Springer
We aimed to explore the cellular action of micro-RNAs that are non-coding-RNAs
modulating gene expression, whose expression is dysregulated in myotonic dystrophy …