Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor

VA Lance, MH Bogart - General and Comparative Endocrinology, 1992 - Elsevier
It has been suggested that sex differentiation in vertebrates is steroid hormone dependent,
that estrogens play a critical role in ovarian differentiation, and that male sex differentiation …

Studies on sex determination in the American alligator alligator mississippiensis

VA Lance, MH Bogart - Journal of Experimental Zoology, 1994 - Wiley Online Library
Estradiol-17β was measured in the plasma and urogenital tissues of male and female
alligator embryos. Hormone levels were generally very low and there was no significant …

Aromatase enzyme activity during gonadal sex differentiation in alligator embryos

CA Smith, PK Elf, JW Lang, JMP Joss - Differentiation, 1995 - Elsevier
Sexual differentiation of the gonads in Alligator mississippiensis and many other oviparous
reptiles is controlled by egg incubation temperature. Estrogens are thought to play a role in …

Sex differences in plasma corticosterone levels in alligator (Alligator mississippiensis) embryos

KF Medler, VA Lance - Journal of Experimental Zoology, 1998 - Wiley Online Library
The sex of alligator embryos is determined by incubation temperature. Females are
produced at temperatures between 29° C and 31° C and males at 33° C. As part of an …

Putative aromatase inhibitor induces male sex determination in a female unisexual lizard and in a turtle with temperature-dependent sex determination

T Wibbels, D Crews - Journal of endocrinology, 1994 - joe.bioscientifica.com
Abstract Treatment of developing embryos of two diverse species of reptiles with fadrozole
(a potent and specific nonsteroidal inhibitor of aromatase activity in mammals) resulted in …

In vitro effects of estradiol and aromatase inhibitor treatment on sex differentiation in Xenopus laevis gonads

S Miyata, T Kubo - General and comparative endocrinology, 2000 - Elsevier
Gonads, still in the indifferent stage, were taken from tadpoles of Xenopus laevis and
maintained in organ culture. These gonads were kept in good condition by frequent …

Effects of incubation temperature and estrogen exposure on aromatase activity in the brain and gonads of embryonic alligators.

MR Milnes Jr, RN Roberts… - Environmental Health …, 2002 - ehp.niehs.nih.gov
During embryogenesis, incubation temperature and the hormonal environment influence
gonadal differentiation of some reptiles, including all crocodilians. Current evidence …

Alligator aromatase cDNA sequence and its expression in embryos at male and female incubation temperatures

WN Gabriel, B Blumberg, S Sutton… - Journal of …, 2001 - Wiley Online Library
In all species of crocodilians, sex is determined not by genetic mechanisms, but by the
temperature at which the egg is incubated. In the American alligator (Alligator …

Yolk steroids decline during sexual differentiation in the alligator

AJ Conley, P Elf, CJ Corbin, S Dubowsky… - General and …, 1997 - Elsevier
The leading explanation of temperature-dependent sex determination (TSD) in reptiles
postulates that (1) ovarian differentiation is directed by estrogen and that (2) estrogen is …

Hormonal reversal and the genetic control of sex differentiation in Xenopus

S Miyata, S Koike, T Kubo - Zoological Science, 1999 - BioOne
Administration of exogenous estradiol between stages 50 and 52 completely feminized the
developing gonads of Xenopus laevis. However, when tadpoles were injected or cultured …