Study on invasion and migration of malignant glioma

XJ Yang, HA Long, YU Sheng-ping - Chinese Journal of Contemporary …, 2018 - cjcnn.org
Glioma shows diffuse infiltrative growth in the brain parenchyma. Even following the
principle of" maximum safe resection", the residual tumor cells are resistant to adjuvant …

Clinical characteristics associated with the intracranial dissemination of gliomas

X Cai, JJ Qin, SY Hao, H Li, C Zeng, SJ Sun… - Clinical Neurology and …, 2018 - Elsevier
Objectives Glioma is the most common malignant tumor of the brain and the intracranial
dissemination of gliomas is the late stage of the development of the tumor. However, there is …

[HTML][HTML] Current Status and Future Perspective in Glioma Invasion Research

T Ohnishi - Brain Sciences, 2024 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor in adults and shows an extremely
poor prognosis, with a median survival of 15 months [1]. The main reason for this poor …

Molecular mechanisms of glioma cell migration and invasion

T Demuth, ME Berens - Journal of neuro-oncology, 2004 - Springer
Gliomas are the most common intracranial tumors. In the US, approximately 15,000 patients
die with glioblastoma per year (CBTRUS 2002). Despite modern diagnostics and treatments …

[HTML][HTML] Regulation of cell proliferation and migration in glioblastoma: new therapeutic approach

Y Kim - Frontiers in oncology, 2013 - frontiersin.org
Glioblastoma is the most aggressive brain cancer with the poor survival rate. A microRNA,
miR-451, and its downstream molecules, CAB39/LKB1/STRAD/AMPK, are known to play a …

Invasion and anti-invasion research of glioma cells in an improved model of organotypic brain slice culture

B Ren, S Yu, C Chen, L Wang, Z Liu, Q Wu… - Tumori …, 2015 - journals.sagepub.com
Aims and background Although glioblastomas infiltrate diffusely into adjacent brain, it is
difficult to unequivocally identify the solitary invading glioma cell. It is necessary to develop …

Therapeutic strategies for glioblastoma

SHU Xiaohong - Journal of Dalian Medical University, 2020 - journal.dmu.edu.cn
Glioblastoma (GBM) is a very destructive nervous system tumor, and it is almost incurable.
The clinical therapeutic strategies of GBM mainly include surgical resection, combined with …

[HTML][HTML] Glioma cell migration and invasion as potential target for novel treatment strategies

U Naumann, P Harter, J Rubel, E Ilina… - Translational …, 2013 - degruyter.com
Diffuse human gliomas constitute a group of most treatment-refractory tumors even if
maximum treatment strategies including neurosurgical resection followed by combined radio …

[PDF][PDF] Metastatic glioblastoma cells use common pathways via blood and lymphatic vessels

S Frank, SA Kuhn, M Brodhun, U Mueller… - Neurol Neurochir …, 2009 - researchgate.net
Generally, gliomas do not metastasize. Therefore, larger series are not available to
investigate the pathways of tumour spread. Here, we present the case of a young man with a …

[HTML][HTML] Overview of the molecular mechanisms of migration and invasion in glioblastoma multiforme

X Liu, JY Chen, Y Chien, YP Yang… - Journal of the Chinese …, 2021 - journals.lww.com
Glioblastoma (GBM) is one of the most devastating cancers, with an approximate median
survival of only 16 months. Although some new insights into the fantastic heterogeneity of …