Tumor cell invasion is a major issue in oncology since it leads to tumor dissemination and
recurrence. In glioblastomas, invasion is an important characteristic, making the disease …

BACKGROUND Glioblastoma has a high degree of malignancy and poor prognosis. It is
common to have in situ recurrence and intracranial metastasis, while extracranial metastasis …

BACKGROUND: Gliomas are the most frequently diagnosed primary intracranial tumours in
adults. This group incorporates astrocytomas, oligodendrogliomas and ependymomas …

Objective To further understand the clinical manifestations and improve clinical diagnosis of
patients with leptomeningeal metastasizing high-grade glioma. Methods Sixteen patients …

INTRODUCTION: A majority of patients with melanoma brain metastases develop multiple
lesions, and these patients show particularly poor prognosis. To develop improved treatment …

Gliomas are the most common primary brain tumors. The most malignant form, the
glioblastoma multiforme (GBM; WHO IV), is characterized by an invasive phenotype, which …

Despite advances in surgical and medical therapy, glioblastoma consistently remains a fatal
disease. Over the last 20 years, no significant increase in survival has been achieved for …

Glioblastoma multiforme (GBM) is well known as the most common malignant primary brain
tumor. It could easily spread into the adjacent or distant brain tissue by infiltration, direct …

The aim of the present study was to investigate the extensive invasion of tumor cells into
normal brain tissue, a life‑threatening feature of malignant gliomas. How invasive tumor cells …

Methods Plasmid BAG was transfected into C6 glioma cell. The cell cycle, cell proliferation,
malignant infiltrative ability of wild and transfected glioma cell were observed. Rat glioma …