Glioblastoma is the most common primary malignant tumor in the neural tissue and a highly
aggressive primary tumor in human. It involves glial cells in 52% of functional brain tissue …

Glioblastomas rarely metastasize outside the CNS. We biologically characterized a case of
secondary glioblastoma associated with extracranial progression and distant metastasis. A …

Results Four patients had metastases within one hemisphere, two had metastases in the
contralateral hemisphere in the period of 5 to 18 months after the first operation. The primary …

Introduction: Surgical resection used to be the mainstay of treatment for glioma. In the last
decade, however, opinion has changed about the goal of surgical resection in treating …

Background: Gliomas are rare and highly malignant tumors of the central nervous system
(CNS) associated with poor survival and high mortality. This study examined the survival of …

Glioblastoma multiforme (GBM) is a WHO grade 4 primary brain tumor with a recalcitrant and
dismal prognosis and a 14-monthmedian survival time. The extracranial spread of GBM is so …

The treatment of glioblastoma, the most prevalent malignant tumor in the central nervous
system, poses considerable challenges. Glioblastoma multiforme, classified as a grade Ⅳ …

Glioblastoma (GBM) is the most common primary intracranial malignancy. The
comprehensive treatment mode based on surgical resection has become the key to improve …

It is well established that glioma cell infiltration extends far beyond the radiological limits of
the tumor. Even more, glioma cells and brain parenchyma develop a functional multicellular …

Tumor cell invasion into the surrounding brain tissue is mainly responsible for the failure of
radical surgical resection and successful treatment, with tumor recurrence as …