DNA vaccines consisted of tumor-associated antigen (TAA) are well suited for
immunotherapy against tumor. The construct can contain TAA fused to an appropriate …

Heat shock proteins (HSPs) are shown to be strong immunoadjuvants, eliciting both innate
and adaptive immune responses against cancers. HSP110 is related in sequence to HSP70 …

The Her2 is one of tumor-associated antigens (TAA), regarded as an ideal target of
immunotherapy. DNA encoding full-length or truncated rat Her2/neu have shown protective …

Several studies have shown that when purified from a tumor, certain heat shock proteins
(HSPs) can function as effective vaccines against the same tumor by virtue of their ability to …

In this study, we explored the protective anti-tumor potency of mouse (self) Hsp70 or Hsp110-
based DNA vaccination approach targeting a tumor-associated antigen, human papilloma …

Tumor cells harbor a repertoire of unique, mutated antigens and shared self-antigens but
generally are incapable of provoking an effective immune response, likely because of …

Hsp70s are a family of ATP-dependent chaperones of relative molecular mass around 70
kDa. Immunization of mice with Hsp70 isolated from tumor tissues has been proved to elicit …

HER2/neu peptide-based vaccines can eliminate human tumors overexpressing the human
epidermal growth factor receptor 2 (HER2/neu), but the efficacy of this therapeutic strategy is …

Antigenic cross‐reactivity between certain tumours has allowed the development of more
widely applicable, major histocompatibility complex‐disparate (allogeneic) whole‐cell …

The rapid growth and ruthless metastasis of tumors demand effective broad immune
responses. Dendritic cells (DCs) are critical in developing tumor vaccines. Recent …