越来越多的证据表明， 雌激素对多种肿瘤的发生发展有促进作用， 不仅包括雌激素靶器官肿瘤，
还包括非靶器官肿瘤。 雌激素通过两种不同的雌激素受体（ estrogen receptor, ER） 亚型 …

Increasing evidence indicates that estrogen promotes tumor growth in both estrogen target
organs and non-target organs. Estrogen regulates cell proliferation and differentiation via …

Lung cancer, of which approximately 85% are non-small cell lung cancer (NSCLC), is the
most leading cause of cancer mortality throughout the world. Despite recent improvements …

Lung cancer is the most common cancer in the world. It is a highly lethal disease in women
and men, and new treatments are urgently needed. Several studies have implicated a role of …

More than 213,000 new cases of lung cancer were diagnosed in the United States in 2007
and more than 160,000 individuals died from their disease (Jemal A, Siegel R, Ward E …

!! 雌激素能通过促进靶细胞增殖" 使致癌物易于发挥作用" 或促进在起始阶段的致癌过程#
在乳腺和子宫内膜的癌变中" 雌激素的促癌作用已得到证明$ &%# 近年研究证实" …

[目的] 探讨雌激素受体拮抗剂在非小细胞肺癌治疗中的作用.[方法] 用逆转录多聚酶链式反应(RT-
PCR) 测定肺腺癌细胞株SPC-A-1 的雌激素受体mRNA (ER-mRNA) 表达 …

e22189 Background: Recent evidence suggests that estrogen signaling is important in the
progression of cancers expressing estrogen receptors (ERs) and may also be involved in …

目的: 用Meta 分析方法评价雌激素受体表达对肺癌预后的价值. 方法: 计算机检索PubMed,
EMBASE, 中国生物医学文献数据库, 万方, 维普和中国期刊全文数据库, 纳入符合标准的文献 …

Thoracic malignancies represent a significant global health burden with incidence and
mortality increasing year by year. Thoracic cancer prognosis and treatment options depend …