支链氨基酸代谢在阿尔茨海默病和其他代谢紊乱的发展中的作用
Alzheimer's disease is an incurable chronic neurodegenerative disorder and the leading
cause of dementia, imposing a growing economic burden upon society. The disease …
cause of dementia, imposing a growing economic burden upon society. The disease …
[HTML][HTML] Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders
Alzheimer's disease is an incurable chronic neurodegenerative disorder and the leading
cause of dementia, imposing a growing economic burden upon society. The disease …
cause of dementia, imposing a growing economic burden upon society. The disease …
Amino acid catabolism in Alzheimer's disease brain: friend or foe?
JWD Griffin, PC Bradshaw - Oxidative medicine and cellular …, 2017 - Wiley Online Library
There is a dire need to discover new targets for Alzheimer's disease (AD) drug development.
Decreased neuronal glucose metabolism that occurs in AD brain could play a central role in …
Decreased neuronal glucose metabolism that occurs in AD brain could play a central role in …
The associations of serum valine with mild cognitive impairment and Alzheimer's disease
Y Xiong, J Therriault, S Ren, X Jing, H Zhang… - Aging Clinical and …, 2022 - Springer
Background The introduction of metabolomics makes it possible to study the characteristic
changes of peripheral metabolism in Alzheimer's disease (AD). Recent studies have found …
changes of peripheral metabolism in Alzheimer's disease (AD). Recent studies have found …
[HTML][HTML] Metabolomic analysis identifies alterations of amino acid metabolome signatures in the postmortem brain of Alzheimer's disease
Despite significant advances in neuroscience research over the past several decades, the
exact cause of AD has not yet fully understood. The metabolic hypothesis as well as the …
exact cause of AD has not yet fully understood. The metabolic hypothesis as well as the …
Serum metabolic signatures for Alzheimer's Disease reveal alterations in amino acid composition and energy metabolism–A validation study
Background: Alzheimer's Disease (AD) is complex and novel approaches are urgently
needed to characterise disease pathology and to aid in diagnosis. Metabolites are the end …
needed to characterise disease pathology and to aid in diagnosis. Metabolites are the end …
Branched-Chain Amino Acids Are Linked with Alzheimer's Disease-Related Pathology and Cognitive Deficits
CA Mullins, AT Kramer, HTTU Shah, RB Gannaban… - 2022 - ttu-ir.tdl.org
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …
Examining the role of branched-chain amino acids in Alzheimer's disease progression
MAB Siddik - 2021 - ttu-ir.tdl.org
Abstract Alzheimer's disease (AD), an age-associated neurodegenerative disorder, is
primarily characterized by accumulated amyloid-beta plaques, neurofibrillary …
primarily characterized by accumulated amyloid-beta plaques, neurofibrillary …
Insulin Resistance and impaired branched-chain amino acid metabolism in Alzheimer's Disease
R Liu, L Zhang, H You - Journal of Alzheimer's Disease, 2023 - content.iospress.com
The pathogenesis of Alzheimer's disease (AD) is complicated and involves multiple
contributing factors. Mounting evidence supports the concept that AD is an age-related …
contributing factors. Mounting evidence supports the concept that AD is an age-related …
[HTML][HTML] Branched-chain amino acids are linked with Alzheimer's disease-related pathology and cognitive deficits
MAB Siddik, CA Mullins, A Kramer, H Shah… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …