[HTML][HTML] 经皮冠状动脉介入治疗术后支架内再狭窄患者血浆Rap1A 水平变化及其机制（ 英文）
高浩东， 匡圆圆， 刘昱博， 张银妆， 王萍… - Journal of Central …, 2023 - ncbi.nlm.nih.gov
目的经皮冠状动脉介入治疗(percutaneous coronary intervention， PCI) 是冠状动脉疾病(
coronary artery disease， CAD) 的主要治疗方法之一， PCI 术后支架内再狭窄(in-stent …
coronary artery disease， CAD) 的主要治疗方法之一， PCI 术后支架内再狭窄(in-stent …
Changes of plasma Rap1A levels in patients with in-stent restenosis after percutaneous coronary intervention and the underlying mechanisms.
H Gao, Y Kuang, Y Liu, Y Zhang, P Wang… - … nan da xue xue bao. Yi …, 2023 - europepmc.org
Objectives Percutaneous coronary intervention (PCI) is one of the most important treatments
for coronary artery disease (CAD). However, in-stent restenosis (ISR) after PCI is a serious …
for coronary artery disease (CAD). However, in-stent restenosis (ISR) after PCI is a serious …
Rap1 induces cytokine production in pro-inflammatory macrophages through NFκB signaling and is highly expressed in human atherosclerotic lesions
Repressor activator protein 1 (Rap1) is essential for maintaining telomere length and
structural integrity, but it also exerts other non-telomeric functions. The present study tested …
structural integrity, but it also exerts other non-telomeric functions. The present study tested …
Inhibitory effects of Rap1GAP overexpression on proliferation and migration of endothelial cells via ERK and Akt pathways
W Li, B Jin, LA Cornelius, B Zhou, X Fu… - Journal of Huazhong …, 2011 - Springer
Rap1 is expressed in human umbilical vein endothelial cells (HUVECs). Rap1-GTPase
activating protein (Rap1GAP), with its specific target, Rap1, has been shown to be important …
activating protein (Rap1GAP), with its specific target, Rap1, has been shown to be important …
Endothelial Rap1 (Ras-association proximate 1) restricts inflammatory signaling to protect from the progression of atherosclerosis
Objective: Small GTPase Rap1 (Ras-association proximate 1) is a novel, positive regulator
of NO release and endothelial function with a potentially key role in mechanosensing of …
of NO release and endothelial function with a potentially key role in mechanosensing of …
Elevated high sensitive C-reactive protein and apelin levels after percutaneous coronary intervention and drug-eluting stent implantation
X Du, J Kang, J Wu, Q Lv, C Tang, C Ma - Journal of Zhejiang University …, 2010 - Springer
Objective Percutaneous coronary intervention (PCI) triggers an acute inflammatory
response, while sirolimus is known to have anti-inflammatory properties; the inflammatory …
response, while sirolimus is known to have anti-inflammatory properties; the inflammatory …
Correlation of pre‐operative circulating inflammatory cytokines with restenosis and rapid angiographic stenotic progression risk in coronary artery disease patients …
J Sun, H Yu, H Liu, D Pu, J Gao, X Jin… - Journal of clinical …, 2020 - Wiley Online Library
Background This study aimed to explore the associations of common inflammatory cytokine
levels with restenosis and rapid angiographic stenotic progression (RASP) risk in coronary …
levels with restenosis and rapid angiographic stenotic progression (RASP) risk in coronary …
IL-1RAP blockade reduces atherosclerosis and limits plaque inflammation
M Mulholland, G Jakobsson… - …, 2022 - atherosclerosis-journal.com
Methods: Methods: Apoe-/-mice fed a high cholesterol diet were treated with either anti-IL-
1RAP antibody (clone: 3A9) or isotype control IgG for six weeks (n= 14/group). After total 10 …
1RAP antibody (clone: 3A9) or isotype control IgG for six weeks (n= 14/group). After total 10 …
Efficacy of perivascular NO-eluting therapies for the prevention of neointimal hyperplasia
SF Najjar, C Pearce, J Eng… - Journal of …, 2006 - journalofsurgicalresearch.com
Background: C-reactive protein (CRP) has been shown to be an inflammatory marker which
predicts cardiovascular disease. However, little is known whether CRP has direct effects on …
predicts cardiovascular disease. However, little is known whether CRP has direct effects on …
Rap1 promotes proliferation and migration of vascular smooth muscle cell via the ERK pathway
Q Li, Y Teng, J Wang, M Yu, Y Li, H Zheng - Pathology-Research and …, 2018 - Elsevier
Background Rap1 is involved in a multitude of cellular signal transduction pathways, which
has extensively been linked to cell proliferation and migration. It has been shown to be …
has extensively been linked to cell proliferation and migration. It has been shown to be …