Magnesium sulfate for neuroprotection: what do we do now?

JR Scott - Obstetrics & Gynecology, 2009 - journals.lww.com
Preterm birth is still a huge problem in modern obstetrics. Because the stakes are so high,
physicians and parents are understandably anxious to do anything possible to prevent …

Fetal neuroprotection by magnesium sulfate: from translational research to clinical application

C Chollat, L Sentilhes, S Marret - Frontiers in neurology, 2018 - frontiersin.org
Despite improvements in perinatal care, preterm birth still occurs regularly and the
associated brain injury and adverse neurological outcomes remain a persistent challenge …

No. 376-magnesium sulphate for fetal neuroprotection

LA Magee, DA De Silva, D Sawchuck, A Synnes… - Journal of Obstetrics and …, 2019 - Elsevier
Objective The objective is to provide guidelines for the use of antenatal magnesium sulphate
for fetal neuroprotection of the preterm infant. Options Antenatal magnesium sulphate …

Magnesium for fetal neuroprotection

SA Reeves, RS Gibbs, SL Clark - American journal of obstetrics and …, 2011 - Elsevier
Available evidence now suggests that magnesium sulfate administered to mothers prior to
early preterm delivery reduces the risk of cerebral palsy in surviving neonates. The …

Magnesium sulfate and fetal neuroprotection: overview of clinical evidence

C Chollat, S Marret - Neural regeneration research, 2018 - journals.lww.com
Antenatal administration of magnesium sulfate is an important part of the neuroprotective
strategy for preterm infants. Strong evidence from five randomized controlled trials and five …

Effects of antenatal exposure to magnesium sulfate on neuroprotection and mortality in preterm infants: a meta-analysis

MM Costantine, SJ Weiner… - Obstetrics & …, 2009 - journals.lww.com
METHODS OF STUDY SELECTION: Randomized controlled trials comparing magnesium
sulfate with placebo/other treatment in patients at risk of preterm delivery were evaluated for …

Effect of magnesium sulfate given for neuroprotection before preterm birth: a randomized, controlled trial

CA Crowther, JE Hiller, LW Doyle… - … & Gynecological Survey, 2004 - journals.lww.com
Some observational studies show that, in very preterm births, magnesium sulfate treatment
is associated with a lower risk of intraventricular hemorrhage (IVH), which predisposes to …

Intrapartum Magnesium for Neuroprotection: Revisiting Gestational Age Criteria

JM Louis, TM Randis - JAMA, 2023 - jamanetwork.com
Prematurity remains a proximate cause of infant morbidity and mortality. 1 Despite extensive
years of research and investment, limited gains have been made in preventing preterm birth …

A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy

DJ Rouse, DG Hirtz, E Thom, MW Varner… - … England Journal of …, 2008 - Mass Medical Soc
Background Research suggests that fetal exposure to magnesium sulfate before preterm
birth might reduce the risk of cerebral palsy. Methods In this multicenter, placebo-controlled …

Magnesium sulfate for neuroprotection

MM Killion - MCN: The American Journal of Maternal/Child …, 2015 - journals.lww.com
Magnesium sulfate administered intravenously to women at risk for early preterm birth can
decrease risk of cerebral palsy in their babies. The regime from one of the larger …