Abstract Interleukin-5 (IL-5) is manifested as its involvement in the process of
atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL …

It is suggested that cholesterol efflux mediated by ATP binding cassette transporter A1
(ABCA1) plays an important role in anti‐atherogenesis. However, the effects of inflammatory …

Background: Interleukin (IL)-18 and IL-12 synergize for the production of interferon (IFN)-γ,
which can downregulate ATP-binding cassette transporter A1 (ABCA1) expression. The aim …

Cholesterol efflux plays a major role in antiatherogenesis, and modification of this process
may provide a new therapeutic approach to cardiovascular disease. Interleukin 8 (IL-8) is …

Objective: Marked anti-atheromatous effects of the anti-inflammatory cytokine interleukin-10
(IL-10) were observed in several lipid-driven animal models of arteriosclerosis. We therefore …

Abstract Interleukin-32 (IL-32) is a pro‑inflammatory cytokine and its effects in various
inflammatory diseases have been investigated. However, the role of IL‑32 on …

Abstract Interleukin (IL)-10 is a prototypical anti-inflammatory cytokine that has been shown
to attenuate atherosclerosis development. In addition to its anti-inflammatory properties, the …

Objective Previous studies suggest that IL-8 has an important role in the regulation of
cholesterol efflux, but whether miRNAs are involved in this process is still unknown. The …

The present study is to investigate whether inflammatory cytokines inhibit ABCA1/ABCG1-
mediated cholesterol efflux by regulating miR-33a-5P in THP-1 macrophages. We used …

Cholesterol-laden monocyte-derived macrophages are phagocytic cells characteristic of
early and advanced atherosclerotic lesions. Interleukin-6 (IL-6) is a macrophage secretory …