Abstract Interleukin-38 (IL-38), a member of the IL-1 family, is known for its anti-inflammatory
properties mediated through ligand signaling in various disease models. It plays a …

Ritonavir, a protease inhibitor used in combination antiretroviral therapy for HIV-1 infection,
is associated with an increased risk of premature atherosclerosis. The aim of the present …

Objective—IL-35 (interleukin-35) is an anti-inflammatory cytokine, which inhibits immune
responses by inducing regulatory T cells and regulatory B cells and suppressing effector T …

Previous studies have demonstrated that inflammatory cytokines such as interleukin-1β (IL-
1β) promote lipid accumulation in human mesangial cells (HMC) by dysregulating the …

Chronic low-grade inflammation contributes to diseases associated with fat tissue
metabolism such as obesity and diabetes by the disturbed production of adipose tissue …

IκBNS is a nuclear IκB protein which negatively regulates nuclear factor-κB activity. We
demonstrated that IκBNS deficiency accelerates atherosclerosis in LDL receptor-deficient …

Aim: The ATP binding cassette transporters A1 and G1 (ABCA1/G1) and scavenger receptor
class B type I (SR-BI) are key molecules in cholesterol efflux and atherogenesis. These …

Pro-and anti-inflammatory cytokines play key roles in the development of atherosclerosis [1].
Interleukin (IL)-1ß is a prototypic inflammatory cytokine, which is predominantly produced by …

To explore the molecular mechanism of exosomal protein CD5L secreted by macrophage to
promote the progression of atherosclerosis. Twenty cases of patients with atherosclerosis …

Although considerable evidence implicates the cytokine interlukin-18 (IL-18) in metabolic
syndrome (MetS), the direct effect of IL-18 on vascular changes of MetS remains unknown …