Efficacy and toxicity of cetuximab with chemotherapy in recurrent and metastatic head and neck cancer: A prospective observational study

S Tiwari, V Goel, MC John, N Patnaik… - Indian Journal of …, 2016 - journals.lww.com
BACKGROUND: In squamous cell carcinoma of the head and neck (SCCHN), epidermal
growth factor receptor is expressed at very high levels. Hence, we have done this study to …

Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro

N Zhang, K Erjala, J Kulmala, X Qiu, M Sundvall… - Radiotherapy and …, 2009 - Elsevier
BACKGROUND AND PURPOSE: For locoregionally advanced HNSCC, chemoradiotherapy
with cisplatin or another platinum compound is considered as one of the standard treatment …

Cetuximab plus radiotherapy in patients with unresectable locally advanced squamous cell carcinoma of head and neck region-A open labelled single arm phase II …

S Dattatreya, C Goswami - Indian Journal of Cancer, 2011 - journals.lww.com
Purpose: To evaluate feasibility, safety and outcome of cetuximab concurrent with
radiotherapy in locally advanced head− neck cancer. Materials and Methods: Between …

Dual epidermal growth factor receptor and human epidermal growth factor receptor 2 inhibition in squamous cell carcinoma of the head and neck; Is the jury still out?

NF Saba, SJ Wong - Journal of Clinical Oncology: Official Journal of …, 2016 - europepmc.org
Dual Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2
Inhibition in Squamous Cell Carcinoma of the Head and Neck; Is the Jury Still Out …

[HTML][HTML] Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial

MS Kies, FC Holsinger, JJ Lee… - Journal of Clinical …, 2010 - ncbi.nlm.nih.gov
Purpose To determine the potential efficacy of combining cetuximab with chemotherapy in
patients with advanced nodal disease, we conducted a phase II trial with induction …

Phase I study of cetuximab in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in patients (pts) with recurrent and/or metastatic squamous cell …

Y Humblet, E Vega-Villegas, R Mesia… - Journal of Clinical …, 2004 - ascopubs.org
5513 Background: The goal of this study was to investigate the safety and efficacy of
cetuximab (Erbitux), an IgG1 monoclonal antibody targeting the EGFR, given in combination …

Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head …

RS Herbst, M Arquette, DM Shin, K Dicke… - Journal of Clinical …, 2005 - ascopubs.org
Purpose This multicenter phase II study was undertaken to define the efficacy and safety of
cetuximab, an antiepidermal growth factor receptor chimeric human and murine monoclonal …

Cetuximab: A critical appraisal of a novel development in the treatment of squamous cell carcinoma of the head and neck

J Gemmill - Journal of Radiotherapy in Practice, 2008 - cambridge.org
Recently published evidence has shown an improvement in locoregional control and a
survival advantage in the treatment of squamous cell carcinomas of the head and neck …

[HTML][HTML] Phase II study of the combination of cetuximab and weekly paclitaxel in the first-line treatment of patients with recurrent and/or metastatic squamous cell …

R Hitt, A Irigoyen, H Cortes-Funes, JJ Grau… - Annals of …, 2012 - Elsevier
Background The efficacy and safety of a novel combination of weekly paclitaxel and the
epidermal growth factor receptor (EGFR) monoclonal antibody cetuximab for the first-line …

Cetuximab in recurrent/metastatic (R&M) squamous cell carcinoma of the head and neck (SCCHN) refractory to first-line platinum-based therapies

JB Vermorken, J Bourhis, J Trigo, M Kies… - Journal of Clinical …, 2005 - ascopubs.org
5505 Background: Patients with R&M SCCHN have a poor prognosis. Patients failing first-
line therapy have few therapeutic options. Cetuximab (Erbitux) is an IgG1 monoclonal …