Title Activation-induced cytidine deaminase is dispensable for virus- mediated liver and skin
tumor development in mouse models( Page 1 Title Activation-induced cytidine deaminase is …

Activation-induced cytidine deaminase (AID) not only promotes immune diversity by
initiating somatic hypermutation and class switch recombination in immunoglobulin genes …

Dendritic cells (DCs) are the most potent antigen-presenting cells and acquire cellular
antigens and danger signals from dying cells to initiate antitumor immune responses via …

Enterovirus 71 (EV71) infection is an endemic disease in Southeast Asia and China. We
have previously shown that EV71 virus causes functional changes in mitochondria. It is …

Complex human-pathogenic retroviruses cause high morbidity and mortality worldwide, but
resist antiviral drugs and vaccine development due to evasion of the immune response. A …

Yeast cytosine deaminase (yCD)-based gene therapy offers the potential for selective
production of the cytotoxic and radiosensitizing drug 5-fluorouracil (5-FU) from the benign …

Abstract 2950 Background; Carcinogenesis is a multistep process that involves the
accumulation of mutations in genes that govern cell proliferation, regeneration and …

Activation-induced cytidine deaminase (AID) is involved in somatic DNA alterations of the
immunoglobulin gene for amplification of immune diversity. The fact that constitutive …

Summary Epstein-Barr virus (EBV), an oncogenic herpesvirus that causes human
malignancies, infects and immortalizes primary human B cells in vitro into indefinitely …

In response to cellular genome breaks, MRE11/RAD50/NBS1 (MRN) activates a global ATM
DNA damage response (DDR) that prevents cellular replication. Here, we show that MRN …