Research advances in TET enzyme and its intermediate product 5hmC
J Wu, X Fang, X Xia, M Zhang - Zhong nan da xue xue bao. Yi xue …, 2019 - europepmc.org
DNA methylation is a significant epigenetic modification mode, which plays an important role
in embryo reprogramming, stem cell differentiation and tumor occurrence. The ten-eleven …
in embryo reprogramming, stem cell differentiation and tumor occurrence. The ten-eleven …
Roles of ten eleven translocation proteins family and 5-hydroxymethylcytosine in epigenetic regulation of stem cells and regenerative medicine
JF Zhao, D Li, Y An - Beijing da xue xue bao. Yi xue ban= Journal of …, 2021 - europepmc.org
The methylation of cytosine is one of the most fundamental epigenetic modifications in
mammalian genomes, and is involved in multiple crucial processes including gene …
mammalian genomes, and is involved in multiple crucial processes including gene …
Structure and function of TET enzymes
X Yin, L Hu, Y Xu - DNA Methyltransferases-Role and Function, 2022 - Springer
Mammalian DNA methylation mainly occurs at the carbon-C5 position of cytosine (5mC).
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
Mechanisms of TET protein-mediated DNA demethylation and its role in the regulation of mouse development.
ZW Jia, SX Gao, YC Zhang, XH Zhang - Yi chuan= Hereditas, 2015 - europepmc.org
TET (ten-eleven translocation) protein family includes three members TET1, TET2 and TET3,
which belong to alpha-ketoglutaric acid (α-KG)-and Fe (2+)-dependent dioxygenase …
which belong to alpha-ketoglutaric acid (α-KG)-and Fe (2+)-dependent dioxygenase …
[HTML][HTML] TET 蛋白家族与5-羟甲基胞嘧啶在干细胞及再生医学表观遗传调控中的作用
赵健芳, 李东, 安阳 - Journal of Peking University (Health Sciences …, 2021 - ncbi.nlm.nih.gov
The methylation of cytosine is one of the most fundamental epigenetic modifications in
mammalian genomes, and is involved in multiple crucial processes including gene …
mammalian genomes, and is involved in multiple crucial processes including gene …
Structure and function of TET enzymes
X Yin, Y Xu - DNA methyltransferases-role and function, 2016 - Springer
Mammalian DNA methylation mainly occurs at the carbon-C5 position of cytosine (5mC).
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
[PDF][PDF] TET enzymes and 5hmC epigenetic mark: new key players in carcinogenesis and progression in gynecological cancers.
AE Zacapala-Gómez… - European Review for …, 2024 - europeanreview.org
DNA methylation is an epigenetic mechanism involving the transfer of a methyl group onto
the C5 position of the cytosine to form 5-methylcytosine (5mC). In general, DNA methylation …
the C5 position of the cytosine to form 5-methylcytosine (5mC). In general, DNA methylation …
Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation
Y Kudo, K Tateishi, K Yamamoto, S Yamamoto… - Cancer …, 2012 - Wiley Online Library
Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic
hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the …
hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the …
Acetylation regulates TET2 stability and enzymatic activity
DNA methylation, one of the key epigenetic modifications in the mammalian genome, plays
fundamental roles in development and disease. Although DNA methylation and DNA …
fundamental roles in development and disease. Although DNA methylation and DNA …
TETology: epigenetic mastermind in action
Cytosine methylation is a well-explored epigenetic modification mediated by DNA
methyltransferases (DNMTs) which are considered “methylation writers”; cytosine …
methyltransferases (DNMTs) which are considered “methylation writers”; cytosine …