In the central nervous system, oligodendrocytes wrap axons with myelin sheaths, which is
essential for rapid transfer of electric signals and their trophic support. In oligodendroglia …

Myelin-forming oligodendrocytes in the vertebrate nervous system co-express the
transcription factor Sox10 and its paralog Sox8. While Sox10 plays crucial roles throughout …

The Sox family of transcription factors have been widely studied in the context of
oligodendrocyte development. However, comparatively little is known about the role of Sox2 …

The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …

The myelin-forming oligodendrocytes are an excellent model to study transcriptional
regulation of specification events, lineage progression, and terminal differentiation in the …

SOX transcription factors have important roles during astrocyte and oligodendrocyte
development, but how glial genes are specified and activated in a sub‐lineage‐specific …

Sox8, Sox9, and Sox10 as transcription factors of subgroup E of the Sox protein family are
essential for many aspects of nervous system development. These SoxE proteins are …

In Schwann cells of the vertebrate peripheral nervous system, induction of myelination and
myelin maintenance both depend on the HMG‐domain‐containing transcription factor …

In the CNS, myelination and remyelination depend on the successful progression and
maturation of oligodendroglial lineage cells, including proliferation and differentiation of …

The role of transcription factor Sox13, which together with Sox5 and Sox6 belongs to the
SoxD family, is only poorly characterized in central nervous system development. Therefore …