Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial …
PP Toth, CM Ballantyne, MH Davidson… - Journal of clinical …, 2012 - Elsevier
BACKGROUND: Recent trends suggest a decreased use of ezetimibe/simvastatin
combination and coadministered ezetimibe plus statin therapies. OBJECTIVE: This analysis …
combination and coadministered ezetimibe plus statin therapies. OBJECTIVE: This analysis …
Real-world data to assess changes in low-density lipoprotein cholesterol and predicted cardiovascular risk after ezetimibe discontinuation post reporting of the …
HE Bays, MD Patel, P Mavros, DR Ramey… - Journal of Clinical …, 2017 - Elsevier
Background The 2008 Ezetimibe and Simvastatin in Hypercholesterolemia Enhances
Atherosclerosis Regression (ENHANCE) study demonstrated ezetimibe+ simvastatin vs …
Atherosclerosis Regression (ENHANCE) study demonstrated ezetimibe+ simvastatin vs …
Combination therapy with ezetimibe/simvastatin versus statin monotherapy for low-density lipoprotein cholesterol reduction and goal attainment in a real-world clinical …
HS Friedman, S Rajagopalan, JP Barnes… - Clinical Therapeutics, 2011 - Elsevier
Background Randomized studies have demonstrated improved attainment of target low-
density lipoprotein cholesterol (LDL-C) values when ezetimibe is combined with statins for …
density lipoprotein cholesterol (LDL-C) values when ezetimibe is combined with statins for …
Achieving goal lipid levels with ezetimibe plus statin add-on or switch therapy compared with doubling the statin dose. A pooled analysis
BM Ambegaonkar, D Tipping, AB Polis, JE Tomassini… - Atherosclerosis, 2014 - Elsevier
Objective: Evaluate the lipid-altering effects of ezetimibe added to ongoing statin therapy,
statin titration, switching from statin monotherapy to a more potent statin or to …
statin titration, switching from statin monotherapy to a more potent statin or to …
A Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: Should …
PP Toth, KC Maki - Journal of Clinical Lipidology, 2008 - lipidjournal.com
In this commentary, the controversies surrounding the Ezetimibe and Simvastatin in
Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial are …
Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial are …
Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult …
T Feldman, M Koren, W Insull Jr, J McKenney… - The American journal of …, 2004 - Elsevier
This study assessed whether the co-administration of ezetimibe and simvastatin would be
more effective than simvastatin monotherapy in allowing high-risk patients to achieve a low …
more effective than simvastatin monotherapy in allowing high-risk patients to achieve a low …
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the …
TA Pearson, MA Denke, PE McBride, WP Battisti… - Mayo Clinic …, 2005 - Elsevier
OBJECTIVE To determine the extent of reduction in low-density lipoprotein cholesterol (LDL-
C) level and improvement in National Cholesterol Education Program Adult Treatment Panel …
C) level and improvement in National Cholesterol Education Program Adult Treatment Panel …
Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin
E Stein, S Stender, P Mata, P Sager, D Ponsonnet… - American heart …, 2004 - Elsevier
BACKGROUND: Despite the efficacy of statins in lowering low-density lipoprotein
cholesterol (LDL-C) levels, many patients who are at high risk for heart disease with …
cholesterol (LDL-C) levels, many patients who are at high risk for heart disease with …
Trends in use of ezetimibe after the ENHANCE trial, 2007 through 2010
JS Ross, SG Frazee, SB Garavaglia… - JAMA internal …, 2014 - jamanetwork.com
Importance Results from the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances
Atherosclerosis Regression (ENHANCE) trial, announced in January 2008, demonstrated …
Atherosclerosis Regression (ENHANCE) trial, announced in January 2008, demonstrated …
Ezetimibe/simvastatin 10/40 mg versus atorvastatin 40 mg in high cardiovascular risk patients with primary hypercholesterolemia: a randomized, double-blind, active …
Background A considerable number of patients with severely elevated LDL-C do not
achieve recommended treatment targets, despite treatment with statins. Adults at high …
achieve recommended treatment targets, despite treatment with statins. Adults at high …