18F-FDG maximum standard uptake value predicts PD-L1 expression on tumor cells or tumor-infiltrating immune cells in non-small cell lung cancer

B Hu, W Chen, Y Zhang, H Shi, D Cheng… - Annals of Nuclear Medicine, 2020 - Springer
Objectives Programmed cell death-ligand 1 (PD-L1) is expressed on tumor cells (TC) and
tumor-infiltrating immune cells (IC). We conducted a retrospective study to investigate the …

[HTML][HTML] Response evaluation after immunotherapy in NSCLC: Early response assessment using FDG PET/CT

S Park, Y Lee, TS Kim, S Kim, JY Han - Medicine, 2020 - journals.lww.com
Response evaluation after immunotherapy in NSCLC: Early resp... : Medicine Response
evaluation after immunotherapy in NSCLC: Early response assessment using FDG PET/CT …

Diagnostic test accuracy of 18F-FDG PET/CT for prediction of programmed death ligand 1 (PD-L1) expression in solid tumours: a meta-analysis

HY Seol, YS Kim, SJ Kim - Clinical Radiology, 2021 - Elsevier
AIM To investigate the predictive value of integrated 2-[18 F]-fluoro-2-deoxy-d-glucose (18 F-
FDG) positron-emission tomography/computed tomography (PET/CT) for the prediction of …

[68Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study

M Zhou, S Xiang, Y Zhao, Y Tang, J Yang, X Yin… - European Journal of …, 2024 - Springer
Abstract Purpose PD-L1 PET imaging, as a non-invasive procedure, can perform a real-time,
dynamic and quantitative analysis of PD-L1 expression at tumor sites. In this study, we …

Perinodular and intranodular radiomic features on 18F-FDG PET/CT images predict PD-L1 status in non-small cell lung cancer

Y Wang, X He, X Song, M Li, D Zhu, F Zhang, Q Chen… - 2022 - researchsquare.com
Background Programmed death-ligand 1 (PD-L1) status can affect the efficacy of
immunotherapy. Based on the link between PD-L1 expression and metabolism, we …

89Zr-Df-anti-PD-L1 for evaluating in vivo PD-L1 level in lung cancer mouse model

A Geller, J Yan, H Guo - 2018 - Soc Nuclear Med
1114 Objectives: Globally, lung cancer is the number one cause of cancer mortality and has
an estimated incidence of 1.3 million new cases every year. Recently, the rise of …

[HTML][HTML] 18F-FDG uptake in PET/CT is a potential predictive biomarker of response to anti-PD-1 antibody therapy in non-small cell lung cancer

K Takada, G Toyokawa, Y Yoneshima, K Tanaka… - Scientific reports, 2019 - nature.com
To examine the association between 18F-fluorodeoxyglucose (18F-FDG) uptake in positron
emission tomography/computed tomography (PET/CT) and the response to anti …

Relationship between SP142 PD‐L1 Expression and 18F‐FDG Uptake in Non‐Small‐Cell Lung Cancer

L Zhao, J Liu, J Shi, H Wang - Contrast Media & Molecular …, 2020 - Wiley Online Library
Objectives. Immune checkpoint blockers constitute the first‐line treatment for advanced non‐
small‐cell lung cancer (NSCLC) with≥ 50% PD‐L1 expression. In NSCLC, PD‐L1 positivity …

Prognostic value of total lesion glycolysis on pretreatment F-18 FDG PET/CT in patients with advanced NSCLC treated with nivolumab

K Ito, R Teng, H Schoder, W Weber - 2018 - Soc Nuclear Med
206 Purpose: Total lesion glycolysis (TLG) and other quantitative parameters derived from
18 F-fludeoxyglucose (FDG) PET/CT have been shown to be prognostic for survival in a …

1161P Can 18F-FDG-PET/CT predict PD-L1 expression in resected non-small cell lung cancer (NSCLC)?

DJ Hughes, S Hunter, D Nonaka, V Goh… - Annals of …, 2021 - annalsofoncology.org
Background Anti-PD-(L) 1 agents play an important role in the management of NSCLC. PD-
L1 analysis by immunohistochemistry is an important biomarker but displays temporospatial …