18F-FDG PET/CT in non-small-cell lung cancer patients: a potential predictive biomarker of response to immunotherapy

L Evangelista, L Cuppari, J Menis… - Nuclear Medicine …, 2019 - journals.lww.com
Aim The aim of this study was to assess the predictive role of fluorine-18-fluorodeoxyglucose
(18 F-FDG) PET/computed tomography (CT) in the evaluation of response to immunotherapy …

Novel biomarkers of dynamic blood PD-L1 expression for immune checkpoint inhibitors in advanced non-small-cell lung cancer patients

Q Yang, M Chen, J Gu, K Niu, X Zhao, L Zheng… - Frontiers in …, 2021 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) have become a high-profile regimen for
malignancy recently. However, only a small subpopulation obtains long-term clinical benefit …

Combining PD-L1 expression and standardized uptake values in FDG-PET/CT can predict prognosis in patients with resectable non–small-cell lung cancer

T Miyazawa, K Otsubo, H Sakai, H Kimura… - Cancer …, 2021 - journals.sagepub.com
Background This study aimed to determine the relationship of programmed death-ligand 1
(PD-L1) expression and standardized uptake values in fluorodeoxyglucose–positron …

Prognostic Potential of Metabolic Activity on 18F-FDG Accumulation in Advanced NSCLC Receiving Combining Chemotherapy Plus PD-1 Blockade

K Hashimoto, K Kaira, H Imai, A Mouri… - Journal of …, 2022 - journals.lww.com
Combined chemotherapy plus programmed death-1 (PD-1) blockade is an established
treatment against patients with advanced non–small cell lung cancer (NSCLC). However, a …

Immuno-PET imaging using 89Zr labeled PD-L1 antibody in non-small cell lung cancer Xenograft

D Li, XH Zhu - 2016 - Soc Nuclear Med
337 Objectives The immune checkpoint, programmed cell death protein-1/programmed cell
death ligand-1 (PD-1/PD-L1) pathway has emerged as a critical target for cancer …

Assessing PD-L1 expression in non-small cell lung cancer patients using68Ga-labeled anti-programmed death ligand-1 (PD-L1) single-domain antibody PET/CT

G Chand, G Cook, D Hughes, L Meszaros, N Wong… - 2020 - Soc Nuclear Med
239 Introduction: The recent rise of checkpoint inhibitor therapy, predominantly programmed
cell death 1 (PD-1)/programmed death ligand-1 (PD-L1) antibodies as a standard care of …

Predictive effect of PD-L1 expression for immune checkpoint inhibitor (PD-1/PD-L1 inhibitors) treatment for non-small cell lung cancer: A meta-analysis

B Zhang, Y Liu, S Zhou, H Jiang, K Zhu… - International …, 2020 - Elsevier
Abstract Background Programmed death-ligand-1 (PD-L1) is a well-known predictive
biomarker in non-small cell lung cancer (NSCLC) patients, however, its accuracy remains …

PD-L1 expression correlation with metabolic parameters of 18F-FDG PET/CT in nonsmall cell lung cancer

E Akgun, R Akyel, AS Koç, B Demirkol, PA Kabalak… - Médecine Nucléaire, 2024 - Elsevier
Objective The aim of this study is to evaluate correlation between Programmed cell death
ligand 1 (PD-L1) mutation status with metabolic parameters derived from 18-F Fluoro-2 …

Artificial Intelligence-Assisted Score Analysis for Predicting the Expression of the Immunotherapy Biomarker PD-L1 in Lung Cancer

A Taylor, S Hernandez, A Kulasinghe… - … Determining Long Term …, 2023 - books.google.com
Programmed cell death ligand 1 (PD-L1) is a critical biomarker for predicting the response to
immunotherapy. However, traditional quantitative evaluation of PD-L1 expression using …

The role of PET molecular imaging in immune checkpoint inhibitor therapy in lung cancer: Precision medicine and visual monitoring

Y Yao, X Zhou, A Zhang, X Ma, H Zhu, Z Yang… - European Journal of …, 2022 - Elsevier
Lung cancer is a malignant tumour originating from the bronchial epithelium or glands of the
lung with high morbidity and mortality. For advanced lung cancer, the lack of effective …