Characterization of the methylation status of five imprinted genes in sheep gametes

A Colosimo, G Di Rocco, V Curini, V Russo… - Animal …, 2009 - Wiley Online Library
Genomic imprinting is a mammalian developmental process that uses epigenetic
mechanisms to induce monoallelic and parental‐specific expression of particular autosomal …

[HTML][HTML] The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA

C Gebert, C Wrenzycki, D Herrmann, D Gröger… - Genomics, 2006 - Elsevier
The insulin-like growth factor 2 gene (IGF2) encodes an essential growth factor and is
imprinted in various mammalian species. Differentially methylated regions (DMRs) are often …

Characterization of differentially methylated regions in 3 bovine imprinted genes: a model for studying human germ-cell and embryo development

T Hansmann, J Heinzmann, C Wrenzycki… - … and Genome Research, 2011 - karger.com
Correct imprinting is crucial for normal fetal and placental development in mammals.
Experimental evidence in animal models and epidemiological studies in humans suggest …

Bovine DNA methylation imprints are established in an oocyte size-specific manner, which are coordinated with the expression of the DNMT3 family proteins

AM O'Doherty, LC O'Shea, T Fair - Biology of reproduction, 2012 - academic.oup.com
A subset of genes, known as imprinted genes, is present in the mammalian genome.
Genomic imprinting governs the monoallelic expression of these genes, depending on …

Methylation status of putative differentially methylated regions of porcine IGF2 and H19

DW Han, YB Im, JT Do, MK Gupta… - Molecular …, 2008 - Wiley Online Library
This study was designed to identify the putative differentially methylated regions (DMRs) of
the porcine imprinted genes insulin‐like growth factor 2 and H19 (IGF2‐H19), and to assess …

[HTML][HTML] Methylation status of differentially methylated regions at Igf2/H19 locus in porcine gametes and preimplantation embryos

CH Park, HS Kim, SG Lee, CK Lee - Genomics, 2009 - Elsevier
The aim of this study was to demonstrate how differential methylation imprints are
established during porcine preimplantation embryo development. For the methylation …

Characterization of the IGF2 imprinted gene methylation status in bovine oocytes during folliculogenesis

AS Mendonça, ALS Guimarães, NMA Silva… - PloS one, 2015 - journals.plos.org
DNA methylation reprogramming occurs during mammalian gametogenesis and
embryogenesis. Sex-specific DNA methylation patterns at specific CpG islands controlling …

[HTML][HTML] DNA methylation in the IGF2 intragenic DMR is re-established in a sex-specific manner in bovine blastocysts after somatic cloning

C Gebert, C Wrenzycki, D Herrmann, D Gröger, J Thiel… - Genomics, 2009 - Elsevier
The recent identification of an intragenic differentially methylated region (DMR) within the
last exon of the bovine Insulin-like growth factor 2 (IGF2) gene provides a diagnostic tool for …

Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle

CL Curchoe, S Zhang, L Yang, R Page… - Animal reproduction …, 2009 - Elsevier
Bos taurus is a good model for embryo biotechnologies such as nuclear transfer. However,
animals produced from these technologies often suffer from large calf syndrome, suggesting …

DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes

E Ivanova, S Canovas, S Garcia-Martínez, R Romar… - Clinical …, 2020 - Springer
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …