[HTML][HTML] 基质辅助激光解吸电离-质谱成像技术(MALDI-MSI) 及其在脑神经性疾病研究中的应用
金涛, 潘本松, 聂洪港 - 计量科学与技术, 2022 - jlkj.nim.ac.cn
大脑是人体内结构最精细, 功能最复杂的高级器官, 其化学物质种类众多, 功能多样,
作用机制复杂. 研究证明, 脑中枢神经系统疾病的病变脑组织都涉及到一些神经分子的改变 …
作用机制复杂. 研究证明, 脑中枢神经系统疾病的病变脑组织都涉及到一些神经分子的改变 …
Matrix-assisted laser desorption/ionization imaging mass spectrometry
N Zaima, T Hayasaka, N Goto-Inoue… - International journal of …, 2010 - mdpi.com
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful tool
that enables the simultaneous detection and identification of biomolecules in analytes …
that enables the simultaneous detection and identification of biomolecules in analytes …
Biomedical application of MALDI mass spectrometry for small‐molecule analysis
JJA van Kampen, PC Burgers… - Mass spectrometry …, 2011 - Wiley Online Library
Matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is an emerging
analytical tool for the analysis of molecules with molar masses below 1,000 Da; that is, small …
analytical tool for the analysis of molecules with molar masses below 1,000 Da; that is, small …
Establishment of imaging mass spectrometry for biological tissues and its application on the proteome analysis of microwave radiated rat hippocampus
L Nian, L Feng, X Bin, G Ya-Bing, L Xiang-Hong… - Chinese Journal of …, 2008 - Elsevier
Imaging mass spectrometry based on matrix assisted laser desorption ionization-time of
flight-mass spectrometry (MALDI-TOF-MS) for biological tissues was established. The key …
flight-mass spectrometry (MALDI-TOF-MS) for biological tissues was established. The key …
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) for in situ analysis of endogenous small molecules in biological samples
H Liu, Y Pan, C Xiong, J Han, X Wang, J Chen… - TrAC Trends in Analytical …, 2022 - Elsevier
Endogenous small molecules play important roles in biological processes and are closely
related to the occurrence and development of many diseases. Profiling of spatial distribution …
related to the occurrence and development of many diseases. Profiling of spatial distribution …
MALDI mass spectrometry imaging of biological structures
N Zaima, N Goto‐Inoue… - Encyclopedia of Analytical …, 2006 - Wiley Online Library
Matrix‐assisted laser desorption/ionization (MALDI) is a 'soft'ionization method which
enables the detection of several molecules including proteins, peptides, amino acids …
enables the detection of several molecules including proteins, peptides, amino acids …
Imaging Method by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) for Tissue or Tumor: A Mini Review
J Wu, Z Rong, P Xiao, Y Li - Processes, 2022 - mdpi.com
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is an advanced
technique that uses minimum fragmented ions from complex molecules for mass …
technique that uses minimum fragmented ions from complex molecules for mass …
Two-step matrix application technique to improve ionization efficiency for matrix-assisted laser desorption/ionization in imaging mass spectrometry
A novel matrix application protocol for direct tissue mass spectrometry is presented. Matrix-
assisted laser desorption/ionization is a popular ionization procedure for direct tissue …
assisted laser desorption/ionization is a popular ionization procedure for direct tissue …
Improvement of sensitivity and reproducibility for imaging of endogenous metabolites by matrix-assisted laser desorption/ionization-mass spectrometry
T Morikawa-Ichinose, Y Fujimura… - Journal of The …, 2019 - ACS Publications
Matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI) is a
powerful technique to visualize the distributions of biomolecules without any labeling. In …
powerful technique to visualize the distributions of biomolecules without any labeling. In …
Review on MALDI mass spectrometry and its application in clinical research
Mass spectrometry has emerged as a powerful analytical tool in various scientific
disciplines, and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI …
disciplines, and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI …