The cancer chemotherapy program was initiated in 1955 and had two well defined
objectives. The first was to develop an organized series of studies which would examine a …

Since 1954, the National Cancer Institute has led a national effort to achieve chemical
control of cancer. This systematic effort was undertaken by the government simply because …

The large number of potentially valuable anticancer agents, the necessity of evaluating
several dosages and various combinations, and the number of patients required for valid …

The discovery and development of anticancer drugs with clinical potential are the
responsibility of the Developmental Therapeutics Program (DTP), Division of Cancer …

The author introduces the subject of modern chemotherapy with reference to developments
within the National Cancer Institute (NCI) and the effort to initiate a national drug …

The Medical Oncology Service of the Department of Medicine reviews the anticancer drugs it
regards as essential for inclusion in the Memorial Hospital Formulary. The discussion …

SINCE 1943, surgery and irradiation as approaches to the cancer problem have been joined
by the gradually evolving field of chemotherapy. The search for chemicals that will affect the …

Publisher Summary This chapter discusses that the consideration of the status of
chemotherapy of cancer in man today is based upon the actual achievement of objective …

I am delighted and honored to participate in your program this afternoon. It is a mark of Dr.
John Ultmann's generosity as president of the American Society of Clinical Oncology, and of …

The methodology of drug development has been the subject of extensive dis cussion by a
relatively small group of individuals in industry and government who have been intimately …