Phase II study of cetuximab in combination with docetaxel in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck after platinum …

M Knoedler, TC Gauler, V Gruenwald, A Matzdorff… - Oncology, 2013 - karger.com
Background: Cetuximab and docetaxel have single-agent activity in squamous cell
carcinoma of the head and neck (SCCHN). The efficacy of their combination was evaluated …

Multicenter phase II study of cetuximab plus docetaxel in 84 patients with recurrent or metastatic, platinum-pretreated SCCHN

MK Knoedler, T Gauler, A Matzdorff… - Journal of Clinical …, 2009 - ascopubs.org
6048 Background: Cetuximab and docetaxel are both active in squamous cell carcinoma of
the head and neck (SCCHN). We investigated the efficacy of cetuximab plus docetaxel as …

Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic …

JB Vermorken, J Trigo, R Hitt, P Koralewski… - Journal of clinical …, 2007 - ascopubs.org
Purpose To evaluate the efficacy and safety of the epidermal growth factor receptor–directed
monoclonal antibody cetuximab administered as a single agent in patients with recurrent …

Randomised phase II study with cetuximab in combination with 5-FU and cisplatin or carboplatin versus cetuximab in combination with paclitaxel and carboplatin for …

S Friesland, G Tsakonas, C Kristensen… - 2018 - ascopubs.org
6032 Background: Platinum-based chemotherapy with cetuximab is the standard of care for
relapsed or metastatic squamous cell carcinoma of the head and neck (SCCHN). The aim of …

Phase I/II study of cetuximab in combination with cisplatin or carboplatin and fluorouracil in patients with recurrent or metastatic squamous cell carcinoma of the head …

J Bourhis, F Rivera, R Mesia, A Awada… - Journal of clinical …, 2006 - ascopubs.org
Purpose This was an open, randomized, multicenter, phase I/II study to investigate the safety
and tolerability of cetuximab in the first-line treatment of recurrent/metastatic squamous cell …

[HTML][HTML] A randomized, phase 2 study of cetuximab plus cisplatin with or without paclitaxel for the first-line treatment of patients with recurrent and/or metastatic …

P Bossi, R Miceli, LD Locati, D Ferrari, S Vecchio… - Annals of …, 2017 - Elsevier
Abstract Background B490 (EudraCT# 2011-002564-24) is a randomized, phase 2b,
noninferiority study investigating the efficacy and safety of first-line cetuximab plus cisplatin …

[HTML][HTML] Randomized phase ii study with cetuximab in combination with 5-FU and cisplatin or carboplatin vs. cetuximab in combination with paclitaxel and carboplatin …

G Tsakonas, L Specht, CA Kristensen, MHC Moreno… - Cancers, 2020 - mdpi.com
Simple Summary The purpose of the CET-MET trial was to find a new platinum-based
chemotherapy regimen in combination with cetuximab for relapsed or metastatic squamous …

Cetuximab in recurrent/metastatic (R&M) squamous cell carcinoma of the head and neck (SCCHN) refractory to first-line platinum-based therapies

JB Vermorken, J Bourhis, J Trigo, M Kies… - Journal of Clinical …, 2005 - ascopubs.org
5505 Background: Patients with R&M SCCHN have a poor prognosis. Patients failing first-
line therapy have few therapeutic options. Cetuximab (Erbitux) is an IgG1 monoclonal …

Phase I study of cetuximab in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in patients (pts) with recurrent and/or metastatic squamous cell …

Y Humblet, E Vega-Villegas, R Mesia… - Journal of Clinical …, 2004 - ascopubs.org
5513 Background: The goal of this study was to investigate the safety and efficacy of
cetuximab (Erbitux), an IgG1 monoclonal antibody targeting the EGFR, given in combination …

Cetuximab monotherapy is active in patients (pts) with platinum-refractory recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN): results of a …

J Trigo, R Hitt, P Koralewski, E Diaz-Rubio… - Journal of Clinical …, 2004 - ascopubs.org
5502 Background: Pts with refractory SCCHN have a poor prognosis with few therapeutic
options. Cetuximab (Erbitux), an IgG1 monoclonal antibody that binds selectively to EGFR …