Nanoparticle-based oral delivery systems for colon targeting: principles and design strategies
L Lu, G Chen, Y Qiu, M Li, D Liu, D Hu, X Gu, Z Xiao - Science Bulletin, 2016 - Elsevier
Colon-targeted oral delivery is crucial for the treatment of colon-related diseases, as this
delivery strategy enables precise drug administration to the diseased site, enhances drug …
delivery strategy enables precise drug administration to the diseased site, enhances drug …
Oral nano-delivery systems for colon targeting therapy
T Zhang, G Zhu, B Lu, Q Peng - Pharmaceutical …, 2017 - ingentaconnect.com
Background: Targeting drug delivery is an attractive research area, as it enables localized
treatment, improves the efficacy of therapeutics and reduces systemic toxicity. Colon …
treatment, improves the efficacy of therapeutics and reduces systemic toxicity. Colon …
Advances in colon-targeted nano-drug delivery systems: challenges and solutions
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
[HTML][HTML] Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue
Colon targeted drug delivery is an active area of research for local diseases affecting the
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …
Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives
Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2023 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …
Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease
Introduction: Inflammatory bowel disease (IBD) is a chronic relapsing idiopathic disease. In
clinical terms, most patients require lifelong medication associated with possible unpleasant …
clinical terms, most patients require lifelong medication associated with possible unpleasant …
Role of nanoparticle size, shape and surface chemistry in oral drug delivery
A Banerjee, J Qi, R Gogoi, J Wong… - Journal of Controlled …, 2016 - Elsevier
Nanoparticles find intriguing applications in oral drug delivery since they present a large
surface area for interactions with the gastrointestinal tract and can be modified in various …
surface area for interactions with the gastrointestinal tract and can be modified in various …
Current Advances of Nanomaterial-Based Oral Drug Delivery for Colorectal Cancer Treatment
N Wang, L Chen, W Huang, Z Gao, M Jin - Nanomaterials, 2024 - mdpi.com
Colorectal cancer (CRC) is a common malignant tumor, and traditional treatments include
surgical resection and radiotherapy. However, local recurrence, distal metastasis, and …
surgical resection and radiotherapy. However, local recurrence, distal metastasis, and …
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …