Achieving goal lipid levels with ezetimibe plus statin add-on or switch therapy compared with doubling the statin dose. A pooled analysis

BM Ambegaonkar, D Tipping, AB Polis, JE Tomassini… - Atherosclerosis, 2014 - Elsevier
Objective: Evaluate the lipid-altering effects of ezetimibe added to ongoing statin therapy,
statin titration, switching from statin monotherapy to a more potent statin or to …

[引用][C] The need for a different cholesterol lowering drug.

G Steiner - The Canadian Journal of Clinical Pharmacology …, 2003 - europepmc.org
The need for a different cholesterol lowering drug. - Abstract - Europe PMC Sign in | Create
an account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us …

[PDF][PDF] Effectiveness and tolerability of ezetimibe co-administered with statins versus statin dose-doubling in high-risk patients with persistent hyperlipidemia: The EZE …

AS Pandey, S Bissonnette, S Boukas… - Archives of Medical …, 2011 - termedia.pl
Study design This was a 6-week, prospective, randomized, open-label trial on patients
recruited from the practices of 241 Canadian general practitioners. Eligible patients signed …

Efficacy, safety and LDL‐C goal attainment of ezetimibe 10 mg–simvastatin 20 mg vs. placebo–simvastatin 20 mg in UK‐based adults with coronary heart disease and …

JV Patel, EA Hughes - International journal of clinical practice, 2006 - Wiley Online Library
It is increasingly accepted that more intensive lipid‐lowering treatment is associated with
greater cardiovascular risk reductions in patients with coronary heart disease (CHD), thus …

Influence of age, gender, and race on the efficacy of adding ezetimibe to atorvastatin vs. atorvastatin up-titration in patients at moderately high or high risk for coronary …

HE Bays, SE Conard, LA Leiter, SR Bird… - International journal of …, 2011 - Elsevier
BACKGROUND: Age, gender, and race are factors that influence atherosclerotic coronary
heart disease (CHD) risk and may conceivably affect the efficacy of lipid-altering drugs …

Ezetimibe added to ongoing statin therapy improves LDL-C goal attainment and lipid profile in patients with diabetes or metabolic syndrome

M Denke, T Pearson, P McBride… - Diabetes and …, 2006 - journals.sagepub.com
This analysis of the Ezetimibe Add-on to Statin for Effectiveness (EASE) trial examined the
effectiveness and safety of ezetimibe 10 mg added to ongoing statin therapy in patients with …

Long-term safety and tolerability of ezetimibe coadministered with simvastatin in hypercholesterolemic patients: a randomized, 12-month double-blind extension study

J Strony, B Yang, ME Hanson… - Current medical research …, 2008 - Taylor & Francis
Objectives: To assess the long-term safety and tolerability and to further evaluate the effect
of ezetimibe plus simvastatin on LDL-C, HDL-C, and triglyceride levels in subjects with …

Comparative Efficacy of Ezetimibe Added to Atorvastatin vs. Uptitration of Atorvastatin in Attainment of Recommended Lipid Targets in Patients at High Risk for …

SE Conard, L Leiter, H Bays, A Shah, J Lin… - Journal of Clinical …, 2009 - lipidjournal.com
Low-density lipoprotein cholesterol (LDL-C) has been identified by treatment guidelines as a
major target for treatment of patients at high risk for coronary heart disease (CHD). Total …

Long-term safety and, tolerability profiles andlipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: A multicenter, randomized …

L Masana, P Mata, C Gagné, W Sirah, M Cho… - Clinical …, 2005 - Elsevier
BACKGROUND:: Ezetimibe (EZE) is a cholesterol-loweringdrug that inhibits absorption of
dietary and biliary cholesterol across the intestinal wall without affecting absorption of bile …

Ezetimibe/Simvastatin 10/40 mg Versus Atorvastatin 40 mg in High Cardiovascular Risk Patients with Primary Hypercholesterolemia

J Triscari, F Civeira, AG Dan, PKH Ling… - Journal of Clinical …, 2011 - lipidjournal.com
Despite substantial lipid-lowering with the use of statin monotherapy, a considerable
number of patients at high cardiovascular risk and/or with severely elevated LDL-C do not …