Reaching goal in hypercholesterolaemia: dual inhibition of cholesterol synthesis and absorption with simvastatin plus ezetimibe
SS Daskalopoulou, DP Mikhailidis - Current medical research and …, 2006 - Taylor & Francis
Lowering serum cholesterol levels reduces the risk of coronary heart disease (CHD)-related
events. Statins are commonly prescribed as first-line treatment but many patients at high-risk …
events. Statins are commonly prescribed as first-line treatment but many patients at high-risk …
[引用][C] Prevention and Rehabilitation-Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with …
CM Ballantyne, N Abate, Z Yuan… - American …, 2005 - … DR, ST LOUIS, MO 63146-3318 …
A Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: Should …
PP Toth, KC Maki - Journal of Clinical Lipidology, 2008 - lipidjournal.com
In this commentary, the controversies surrounding the Ezetimibe and Simvastatin in
Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial are …
Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial are …
Effect of ezetimibe in patients who cannot tolerate statins or cannot get to the low density lipoprotein cholesterol target despite taking a statin
IF Gazi, SS Daskalopoulou, DR Nair… - … medical research and …, 2007 - Taylor & Francis
Background: Recent guidelines underline the need for high-risk patients to reach strict low
density lipoprotein cholesterol (LDL‑C) targets (1.8–2.6 mmol/L; 70–100 mg/dL), and …
density lipoprotein cholesterol (LDL‑C) targets (1.8–2.6 mmol/L; 70–100 mg/dL), and …
Consistency of lipid-altering effects of ezetimibe/simvastatin across gender, race, age, baseline low density lipoprotein cholesterol levels, and coronary heart disease …
L Ose, A Shah, MJ Davies, J Rotonda… - … medical research and …, 2006 - Taylor & Francis
Background: The combination tablet containing ezetimibe and simvastatin (EZE/SIMVA),
inhibits both the intestinal absorption and endogenous production of cholesterol, providing …
inhibits both the intestinal absorption and endogenous production of cholesterol, providing …
Efficacy and safety of ezetimibe added on to atorvastatin (40 mg) compared with uptitration of atorvastatin (to 80 mg) in hypercholesterolemic patients at high risk of …
The percentage of change from baseline in low-density lipoprotein (LDL) cholesterol after
the addition of ezetimibe 10 mg to atorvastatin 40 mg was compared with uptitration to …
the addition of ezetimibe 10 mg to atorvastatin 40 mg was compared with uptitration to …
[引用][C] Ezetimibe & Atorvastatin Coadministration vs Atorvastatin Uptitration or Switching to Rosuvastatin in Primary Hypercholesterolemic Patients at High …
HE Bays, M Averna, C Majul… - Journal of Clinical …, 2013 - lipidjournal.com
Many patients at high risk for atherosclerotic coronary heart disease (CHD) do not achieve
guideline-recommended LDL-C levels; higher statin doses may not be appropriate or …
guideline-recommended LDL-C levels; higher statin doses may not be appropriate or …
Baseline low-density lipoprotein cholesterol and clinical outcomes of combining ezetimibe with statin therapy in IMPROVE-IT
K Oyama, RP Giugliano, MA Blazing, JG Park… - Journal of the American …, 2021 - jacc.org
Background The 2018 US cholesterol management guideline recommends additional lipid-
lowering therapy with ezetimibe for secondary prevention in very high-risk patients with low …
lowering therapy with ezetimibe for secondary prevention in very high-risk patients with low …
[引用][C] Variability of the LDL-C Lowering Response to Ezetimibe and Ezetimibe+ Statin Therapy in Hypercholesterolemic Patients
JE Tomassini, J Lin, AB Polis, A Shah… - Journal of Clinical …, 2013 - lipidjournal.com
The response to lipid-lowering therapy can vary among individuals with cardiovascular risk
due to various inherited and acquired patient characteristics. This may impact their ability to …
due to various inherited and acquired patient characteristics. This may impact their ability to …