慢性C 型肝炎治療新利器: 全基因型直接抗病毒藥

陳玟苑, 徐雅玫, 徐麗珍, 簡素玉 - 臺灣臨床藥學雜誌, 2020 - airitilibrary.com
近幾年慢性C 型肝炎(hepatitis C virus, HCV) 的治療用藥迅速發展, 注射型的干擾素時代已經
過去, 取而代之的是全口服劑型的直接抗病毒藥品(direct-acting antivirals, DAAs) …

The era of direct-acting antivirals has begun: the beginning of the end for HCV?

ML Vachon, DT Dieterich - Seminars in liver disease, 2011 - thieme-connect.com
The year 2011 marks the dawn of the new era of direct-acting antivirals for hepatitis C. For
the first time since 1998, the US Food and Drug Administration approved two new antiviral …

[PDF][PDF] New horizons in hepatitis C antiviral therapy with direct‐acting antivirals

A Aghemo, R De Francesco - Hepatology, 2013 - Wiley Online Library
Most direct‐acting antivirals (DAAs) that are being developed as therapy against hepatitis C
virus target the NS3/4A protease, the NS5A protein, and the NS5B polymerase. The latter …

Recent advances in the treatment of hepatitis C virus infection for special populations and remaining problems

G Suda, N Sakamoto - Journal of Gastroenterology and …, 2021 - Wiley Online Library
Hepatitis C virus (HCV) infection is one of the primary causes of liver cirrhosis,
hepatocellular carcinoma (HCC), and liver transplantation (LT). The rate of HCV infection is …

[HTML][HTML] New direct-acting antivirals for the treatment of chronic hepatitis C

숙향정 - Journal of the Korean Medical Association, 2015 - synapse.koreamed.org
The successful development of direct-acting antivirals (DAA) represents a breakthrough in
the treatment of hepatitis C virus (HCV) infection. Pegylated interferon alpha and ribavirin …

[HTML][HTML] Real-world efficacy and safety of direct-acting antiviral drugs in patients with chronic hepatitis C and inherited blood disorders

I Ruiz, S Fourati, A Ahmed-Belkacem… - European Journal of …, 2021 - journals.lww.com
Background Patients with inherited blood disorders (IBLD) have a high risk of hepatitis C
virus (HCV) infection. The aim of this work was to assess the efficacy and safety of HCV …

Efficacy and safety of direct‐acting antiviral therapies and baseline predictors for treatment outcomes in hepatitis C patients: A multicenter, real‐world study in …

Z Xie, K Deng, Y Xia, C Zhang, M Xu… - Journal of Medical …, 2022 - Wiley Online Library
The data on direct‐acting antivirals (DAAs) in chronic hepatitis C (CHC) patients in southern
China with multiple genotypes circulating are limited. This study aims to evaluate the efficacy …

[PDF][PDF] 慢性C 型肝炎治療的新進展: 從干擾素到直接抗病毒藥物

劉俊人, 許景盛, 高嘉宏 - 內科學誌, 2012 - tsim.org.tw
摘要C 型肝炎病毒感染一直是全球公共衛生上的重要課題. 慢性C 型肝炎的治療在近年來已經有
了長足的進步, 亞太地區在這個研究領域上也有許多深入的研究與新的發現. 本文針對這個主題 …

[HTML][HTML] Real-world effectiveness of direct-acting antiviral agents for chronic hepatitis C in Taiwan: Real-world data

CM Hong, CH Liu, TH Su, HC Yang, PJ Chen… - Journal of Microbiology …, 2020 - Elsevier
Background/purpose Treatment of chronic hepatitis C (CHC) has entered a new era since
the introduction of direct-acting antiviral agents (DAAs). Numerous clinical trials have shown …

Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: a clinical randomized study

C Sølund, ES Andersen, B Mössner… - European journal of …, 2018 - journals.lww.com
Objective New potent direct-acting antiviral (DAA) regimens against hepatitis C virus have
been approved in recent years. However, information about the rate of adverse events (AEs) …